We investigated the relationship between the reversibility of airflow limitation, the
concentration of nitric oxide (NO) in exhaled air, and the inflammatory cells in the sputum of …

A reliable predictor of benefit from corticosteroid treatment in patients with chronic airflow
limitation is needed. In a single-blind, sequential crossover trial of placebo and prednisone …

Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
obstruction and a neutrophilic inflammation. Exhaled nitric oxide (NO) may be a marker of …

Study objectives: The management of stable patients with COPD depends on the severity of
symptoms and airflow limitation. Regarding inflammation, corticosteroids are the only …

To determine whether patients with fixed airflow obstruction have distinct pathologic and
functional characteristics depending on a history of either asthma or chronic obstructive …

Study objectives We examined the effects of glucocorticoids on airway inflammation and its
association with the reversibility of airflow obstruction in response to oral glucocorticoid …

Background Some patients with chronic obstructive pulmonary disease (COPD) respond to
corticosteroid therapy. Whether these patients have different airway pathology from other …

Eosinophilic inflammation has been observed in the airways of patients with chronic
obstructive pulmonary disease (COPD). A subset of patients clinically diagnosed as having …

BACKGROUND: Both smokers and patients with asthma can experience fixed airflow
obstruction, which is associated with distinctive patterns of airway pathology. The influence …

The aim of the study was to evaluate the exhaled nitric oxide (FENO) in clinically stable
chronic obstructive pulmonary disease (COPD), its relationship to the severity of the disease …