Resistance of mice of the 129 background to Yersinia pestis maps to multiple loci on chromosome 1

M Tencati, RI Tapping - Infection and immunity, 2016 - Am Soc Microbiol
Yersinia pestis is a Gram-negative bacterium that is the causative agent of bubonic and
pneumonic plague. It is commonly acquired by mammals such as rodents and humans via …

The Resistance of BALB/cJ Mice to Yersinia pestis Maps to the Major Histocompatibility Complex of Chromosome 17

JK Turner, MM McAllister, JL Xu… - Infection and …, 2008 - Am Soc Microbiol
Yersinia pestis, the causative agent of plague, has been well studied at the molecular and
genetic levels, but little is known about the role that host genes play in combating this highly …

Mice Naturally Resistant to Yersinia pestis Δpgm Strains Commonly Used in Pathogenicity Studies

YHK Congleton, CR Wulff, EJ Kerschen… - Infection and …, 2006 - Am Soc Microbiol
We report that females of some substrains of inbred mouse strain 129 are resistant to
systemic plague due to conditionally virulent Δ pgm strains of Yersinia pestis; however, fully …

Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors

L Chevallier, C Blanchet, J Jaubert, E Pachulec… - Genes & …, 2013 - nature.com
We have previously described SEG/Pas as the first mouse inbred strain able to survive
subcutaneous injection of virulent Yersinia pestis, the agent of plague, and we identified …

Mus spretus SEG/Pas mice resist virulent Yersinia pestis, under multigenic control

C Blanchet, J Jaubert, E Carniel, C Fayolle, G Milon… - Genes & …, 2011 - nature.com
Laboratory mice are well known to be highly susceptible to virulent strains of Yersinia pestis
in experimental models of bubonic plague. We have found that Mus spretus-derived …

The Life Stage of Yersinia pestis in the Flea Vector Confers Increased Resistance to Phagocytosis and Killing by Murine Polymorphonuclear Leukocytes

JL Spinner, BJ Hinnebusch - Advances in Yersinia Research, 2012 - Springer
Yersinia pestis, the bacterial agent of plague, is transmitted to a mammalian host through the
bite of an infected flea. After deposition into the dermis, Y. pestis must subvert or prevent an …

Early systemic bacterial dissemination and a rapid innate immune response characterize genetic resistance to plague of SEG mice

CE Demeure, C Blanchet, C Fitting… - Journal of Infectious …, 2012 - academic.oup.com
Background. Although laboratory mice are usually highly susceptible to Yersinia pestis, we
recently identified a mouse strain (SEG) that exhibited an exceptional capacity to resist …

Delineation and Analysis of Chromosomal Regions Specifying Yersinia pestis

A Derbise, V Chenal-Francisque, C Huon… - Infection and …, 2010 - Am Soc Microbiol
Yersinia pestis, the causative agent of plague, has recently diverged from the less virulent
enteropathogen Yersinia pseudotuberculosis. Its emergence has been characterized by …

An additional step in the transmission of Yersinia pestis?

WR Easterday, KL Kausrud, B Star, L Heier… - The ISME …, 2012 - academic.oup.com
Plague, caused by the bacterium Yersinia pestis, is a mammalian vector-borne disease,
transmitted by fleas that serve as the vector between rodent hosts. For many pathogens …

Subtle genetic modifications transformed an enteropathogen into a flea-borne pathogen

E Carniel - Proceedings of the National Academy of …, 2014 - National Acad Sciences
Yersinia pestis is the etiological agent of plague, one of the most devastating diseases in
human history. Because of the identification of the plague bacillus, the understanding of its …