Overexpression of polycomb protein BMI-1 in human specimens of breast, ovarian, endometrial and cervical cancer

A Honig, C Weidler, S Häusler… - Anticancer …, 2010 - ar.iiarjournals.org
Introduction: The polycomb group (PcG) proteins form chromatin-modifying complexes that
are commonly deregulated in cancer. The PcG protein BMI-I is overexpressed by various …

Expression of bmi-1 protein in cervical, breast and ovarian cancer

MM Gavrilescu, AM Todosi, MG ANITEI… - The Medical-Surgical …, 2012 - revmedchir.ro
B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) is a member of
polycomb group, which participates in axial patterning, hematopoiesis, cell cycle regulation …

Overexpression of Bmi-1 in uterine cervical cancer: correlation with clinicopathology and prognosis

X Zhang, CX Wang, C Zhu, J Zhang, S Kan… - International Journal of …, 2010 - ijgc.bmj.com
Introduction: B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) is a
member of polycomb group, which participates in axial patterning, hematopoiesis, cell cycle …

Polycomb group protein Bmi1 expression in colon cancers predicts the survival

J Du, Y Li, J Li, J Zheng - Medical Oncology, 2010 - Springer
Colorectal cancer is the second leading cause of cancer-related death in the United States
and the fourth leading cause worldwide. Currently, there is still no excellent predictor of the …

[HTML][HTML] Aberrantly elevated Bmi1 promotes cervical cancer tumorigenicity and tumor sphere formation via enhanced transcriptional regulation of Sox2 genes

R Xu, L Chen, WT Yang - Oncology Reports, 2019 - spandidos-publications.com
The exact molecular mechanisms underlying cervical tumorigenesis are poorly understood.
Polycomb complex protein Bmi1 (Bmi1) is involved in the malignant transformation and …

[HTML][HTML] Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain

AK Yadav, AA Sahasrabuddhe, M Dimri, PV Bommi… - Molecular cancer, 2010 - Springer
Abstract Background The polycomb group (PcG) protein BMI1 is an important regulator of
development. Additionally, aberrant expression of BMI1 has been linked to cancer stem cell …

Bmi‐1 is critical for the proliferation and invasiveness of gastric carcinoma cells

W Li, Y Li, Y Tan, K Ma, J Cui - Journal of gastroenterology and …, 2010 - Wiley Online Library
Abstract Background and Aim: Bmi‐1 is a transcriptional repressor belonging to the
Polycomb group and is associated with the cell proliferation and carcinogenesis of a variety …

[HTML][HTML] BMI‑1, a promising therapeutic target for human cancer

MC Wang, CL Li, J Cui, M Jiao, T Wu… - Oncology …, 2015 - spandidos-publications.com
BMI‑1 oncogene is a member of the polycomb‑group gene family and a transcriptional
repressor. Overexpression of BMI‑1 has been identified in various human cancer tissues …

Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma

H Wang, K Pan, H Zhang, D Weng, J Zhou, J Li… - Journal of cancer …, 2008 - Springer
Purpose Recent studies have identified polycomb-group gene Bmi-1 as oncogene in the
generation of mouse pre-cell lymphomas, and overexpression of Bmi-1 has been found in …

[HTML][HTML] Circulating Bmi-1 mRNA as a possible prognostic factor for advanced breast cancer patients

J Silva, V García, JM García, C Peña… - Breast Cancer …, 2007 - Springer
Abstract Introduction Deregulation of Polycomb member Bmi-1 is involved in cell
proliferation and human oncogenesis. Modulation of Bmi-1 is found in several tumor tissues …