Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin
J Handzlik, E Szymańska, S Alibert, J Chevalier… - Bioorganic & medicinal …, 2013 - Elsevier
A series of amine-alkyl derivatives of 5-arylidenehydantoin 3–21 was evaluated for their
ability to improve antibiotic effectiveness in two strains of Gram-negative Enterobacter …
ability to improve antibiotic effectiveness in two strains of Gram-negative Enterobacter …
Amine–alkyl derivatives of hydantoin: New tool to combat resistant bacteria
J Handzlik, E Szymańska, J Chevalier… - European journal of …, 2011 - Elsevier
A series of new 5, 5-diphenylhydantoin derivatives with various amine–alkyl terminal
fragments at N1-position were synthesized. Then a series of twenty-eight compounds with …
fragments at N1-position were synthesized. Then a series of twenty-eight compounds with …
[HTML][HTML] Efflux pump blockers in Gram-negative bacteria: The new generation of hydantoin based-modulators to improve antibiotic activity
E Otręebska-Machaj, J Chevalier, J Handzlik… - Frontiers in …, 2016 - frontiersin.org
Multidrug resistant (MDR) bacteria are an increasing health problem with the shortage of
new active antibiotic agents. Among effective mechanisms that contribute to the spread of …
new active antibiotic agents. Among effective mechanisms that contribute to the spread of …
Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant …
J Chevalier, A Mahamoud, M Baitiche, E Adam… - International journal of …, 2010 - Elsevier
Amongst the three series of quinazoline derivatives synthesised and studied in this work,
some molecules increase the antibiotic susceptibility of Gram-negative bacteria presenting …
some molecules increase the antibiotic susceptibility of Gram-negative bacteria presenting …
[HTML][HTML] Molecular insights into an antibiotic enhancer action of new morpholine-containing 5-arylideneimidazolones in the fight against MDR bacteria
A Kaczor, K Witek, S Podlewska, V Sinou… - International Journal of …, 2021 - mdpi.com
In the search for an effective strategy to overcome antimicrobial resistance, a series of new
morpholine-containing 5-arylideneimidazolones differing within either the amine moiety or at …
morpholine-containing 5-arylideneimidazolones differing within either the amine moiety or at …
Synergy Potential of Indole Alkaloids and Its Derivative against Drug‐resistant Escherichia coli
Antibacterial and synergy potential of naturally occurring indole alkaloids (IA): 10‐methoxy
tetrahydroalstonine (1), isoreserpiline (2), 10 and 11 demethoxyreserpiline (3), reserpiline …
tetrahydroalstonine (1), isoreserpiline (2), 10 and 11 demethoxyreserpiline (3), reserpiline …
Design and synthesis of novel arylurea derivatives of aryloxy (1-phenylpropyl) alicyclic diamines with antimicrobial activity against multidrug-resistant Gram-positive …
V Canale, J Czekajewska, K Klesiewicz… - European Journal of …, 2023 - Elsevier
The alarming increase in the resistance of bacteria to the currently available antibiotics
necessitates the development of new effective antimicrobial agents that are active against …
necessitates the development of new effective antimicrobial agents that are active against …
New Ianthelliformisamine derivatives as antibiotic enhancers against resistant Gram-negative bacteria
C Pieri, D Borselli, C Di Giorgio, M De Meo… - Journal of medicinal …, 2014 - ACS Publications
A series consisting of ianthelliformisamimes A, B, and C as well as its synthetic analogues
was prepared in high chemical yield, from 27 to 91%, using peptide coupling as the key …
was prepared in high chemical yield, from 27 to 91%, using peptide coupling as the key …
4‐Hydroxy‐α‐Tetralone and its Derivative as Drug Resistance Reversal Agents in Multi Drug Resistant Escherichia coli
The purpose of present investigation was to understand the drug resistance reversal
mechanism of 4‐hydroxy‐α‐tetralone (1) isolated from Ammannia spp. along with its semi …
mechanism of 4‐hydroxy‐α‐tetralone (1) isolated from Ammannia spp. along with its semi …
[HTML][HTML] 5-arylideneimidazolones with amine at position 3 as potential antibiotic adjuvants against multidrug resistant bacteria
A Kaczor, K Witek, S Podlewska, J Czekajewska… - Molecules, 2019 - mdpi.com
Searching for new chemosensitizers of bacterial multidrug resistance (MDR), chemical
modifications of (Z)-5-(4-chlorobenzylidene)-2-(4-methylpiperazin-1-yl)-3H-imidazol-4 (5H) …
modifications of (Z)-5-(4-chlorobenzylidene)-2-(4-methylpiperazin-1-yl)-3H-imidazol-4 (5H) …