ARX (the aristaless-related homeobox gene) is a transcription factor that participates in the
development of GABAergic and cholinergic neurons in the forebrain. Many ARX mutations …

Mutations in the X-linked aristaless-related homeobox gene (ARX) have been linked to
structural brain anomalies as well as multiple neurocognitive deficits. The generation of Arx …

Abstract Mutations in the Aristaless-Related Homeobox (ARX) gene cause structural
anomalies of the brain, epilepsy, and neurocognitive deficits in children. During forebrain …

Mental retardation (MR) and epilepsy are both heterogeneous syndromes based on
dysfunction in the brain and they are often closely associated. Hence, there should be some …

Mutations in the Aristaless-related homeobox (ARX) gene are one of the most frequent
causes of X-linked intellectual disability (ID). Several missense mutations, clustered in the …

Purpose: ARX, the aristaless‐related homeobox gene, is implicated in cerebral, testicular,
and pancreatic development. ARX mutations are associated with various forms of epilepsy …

Genetic investigations of X-linked intellectual disabilities have implicated the ARX
(Aristaless-related homeobox) gene in a wide spectrum of disorders extending from …

Aristaless-related homeobox (ARX) gene mutations cause a diverse spectrum of disorders
of the human brain, including lissencephaly, various forms of epilepsy and non-syndromic …

Mutations in the aristaless-related homeobox (ARX) gene are associated with multiple
neurologic disorders in humans. Studies in mice indicate Arx plays a role in neuronal …

Genetic investigations of X-linked mental retardation have demonstrated the implication of
ARX in a wide spectrum of disorders extending from phenotypes with severe neuronal …