Neuronal macroautophagy: from development to degeneration
Macroautophagy, a lysosomal pathway responsible for the turnover of organelles and long-
lived proteins, has been regarded mainly as an inducible process in neurons, which is …
lived proteins, has been regarded mainly as an inducible process in neurons, which is …
Autophagy in neurons a review
KE Larsen, D Sulzer - Histology and histopathology, 2002 - digitum.um.es
Macroautophagy is a process of regulated turnover of cellular constituents that occurs during
development and under conditions of stress such as starvation. Defects in autophagy have …
development and under conditions of stress such as starvation. Defects in autophagy have …
[PDF][PDF] The different autophagy degradation pathways and neurodegeneration
A Fleming, M Bourdenx, M Fujimaki, C Karabiyik… - Neuron, 2022 - cell.com
The term autophagy encompasses different pathways that route cytoplasmic material to
lysosomes for degradation and includes macroautophagy, chaperone-mediated autophagy …
lysosomes for degradation and includes macroautophagy, chaperone-mediated autophagy …
Autophagy deregulation in neurodegenerative diseases–recent advances and future perspectives
ZH Cheung, NY Ip - Journal of neurochemistry, 2011 - Wiley Online Library
J. Neurochem.(2011) 118, 315–316. Abstract Autophagy is an evolutionarily conserved
homeostatic process for the turnover of cellular contents, organelles and misfolded proteins …
homeostatic process for the turnover of cellular contents, organelles and misfolded proteins …
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
Macroautophagy, a major pathway for organelle and protein turnover, has been implicated
in the neurodegeneration of Alzheimer's disease (AD). The basis for the profuse …
in the neurodegeneration of Alzheimer's disease (AD). The basis for the profuse …
Autophagy and its normal and pathogenic states in the brain
A Yamamoto, Z Yue - Annual review of neuroscience, 2014 - annualreviews.org
Autophagy is a conserved catabolic process that delivers the cytosol and cytosolic
constituents to the lysosome. Its fundamental role is to maintain cellular homeostasis and to …
constituents to the lysosome. Its fundamental role is to maintain cellular homeostasis and to …
Mechanism and regulation of autophagy and its role in neuronal diseases
Z Hu, B Yang, X Mo, H Xiao - Molecular neurobiology, 2015 - Springer
Autophagy is a constitutive lysosomal catabolic pathway that degrades damaged organelles
and protein aggregates. Neuronal survival is highly dependent on autophagy due to its post …
and protein aggregates. Neuronal survival is highly dependent on autophagy due to its post …
[HTML][HTML] The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
Autophagy is a tightly regulated cell self-eating process. It has been shown to be associated
with various neuropathological conditions and therefore, traditionally known as a stress …
with various neuropathological conditions and therefore, traditionally known as a stress …
Autophagy in neuronal cells: general principles and physiological and pathological functions
Autophagy delivers cytoplasmic components and organelles to lysosomes for degradation.
This pathway serves to degrade nonfunctional or unnecessary organelles and aggregate …
This pathway serves to degrade nonfunctional or unnecessary organelles and aggregate …
[HTML][HTML] Recent progress in the role of autophagy in neurological diseases
T Meng, S Lin, H Zhuang, H Huang, Z He, Y Hu… - Cell Stress, 2019 - ncbi.nlm.nih.gov
Autophagy (here refers to macroautophagy) is a catabolic pathway by which large protein
aggregates and damaged organelles are first sequestered into a double-membraned …
aggregates and damaged organelles are first sequestered into a double-membraned …