Background and Objective The presence of lipid-specific immunoglobulin M bands in the
cerebrospinal fluid (CSF) predicts an aggressive course in patients with relapsing–remitting …

Background and purpose: Interferon beta and Glatiramer acetate are safe
immunomodulatory treatments (IT) for multiple sclerosis (MS), but not always effective. New …

Oligoclonal IgM bands (OCMB) against myelin lipids predict an aggressive multiple sclerosis
(MS) course. However, the clinical significance of OCMB without lipid specificity, present in …

Objective To determine the best method to measure intrathecal immunoglobulin (Ig) M
synthesis (ITMS), a biomarker of worse prognosis in multiple sclerosis (MS). We compared …

Objective: To determine whether peripheral immune responses as measured by serum
antigen arrays are linked to cerebral MRI measures of disease severity in multiple sclerosis …

The objective of this study was to investigate whether the presence of lipid-specific
oligoclonal IgM bands (LS-OCMB) in cerebrospinal fluid (CSF) influences the response to …

Multiple sclerosis (MS) is an autoimmune disease that targets the central nervous system
(CNS). MS initially follows a relapsing–remitting course (RRMS) in which acute attacks are …

Oligoclonal IgG bands (OCGB) are characteristic of multiple sclerosis (MS). Most patients
show OCGB exclusively in cerebrospinal fluid (CSF). Others have serum bands with …

Oligoclonal IgM bands restricted to cerebrospinal fluid are an unfavorable prognostic marker
in MS, the most common demyelinating disease of the CNS. We have attempted to identify …

Objective To evaluate the value of serum immunoglobulin G (IgG) and immunoglobulin M
(IgM) antibodies reactive with phosphatidylcholine (PC) and lactosylceramide (LC) as …