Obesity and type II diabetes are characterized by insulin resistance in peripheral tissues. A
high caloric intake combined with a sedentary lifestyle is the leading cause of these …

Obesity and type II diabetes are characterized by insulin resistance in peripheral tissues. A
high caloric intake combined with a sedentary lifestyle is the leading cause of these …

The aim of this review is to summarize the mechanisms underlying insulin resistance in
morbid obesity. Glucose regulation by insulin depends on the suppression of endogenous …

The prevalence of diabetes and obesity continues to increase. It is therefore important to
identify the pathophysiology underlying these disorders. An inability of insulin to stimulate …

The prevalence of obesity continues to rise worldwide despite evidence-based public health
recommendations. The promise to adopt a healthy lifestyle is increasingly important for …

Since the discovery of leptin, the adipocyte and its products have been the subject of
intensive research. Thus, it has been demonstrated that adipose tissue plays a central role …

Adipose tissue is a complex endocrine organ with an intricate role in whole body
homeostasis. Beyond storing energy, adipose tissue is fundamental in numerous processes …

Immoderate energy intake, a sedentary lifestyle, and aging have contributed to the
increased prevalence of obesity, sarcopenia, metabolic syndrome, type 2 diabetes, and …

Otyłość, jako problem ogólnoświatowy, stanowi poważne zagrożenie dla zdrowia ludzi oraz
obniża jakość ich życia. Nadmierne nagromadzenie tkanki tłuszczowej prowadzi do …

In mammals, energy storage and release is crucial for survival in the face of intermittent food
availability. The adipose tissue fulfils this need through its unique capacity to store energy in …