Evaluation of zinc-oxide nanoparticles effect on treatment of diabetes in streptozotocin-induced diabetic rats

M Afify, N Samy, NA Hafez… - Egyptian Journal of …, 2019 - ejchem.journals.ekb.eg
Aim: to produce unique products with novel properties, to manipulate materials at the nano-
scale level. Nanoparticles demonstrate novel or improved characteristics which are …

Therapeutic efficacy of zinc oxide nanoparticles in diabetic rats.

MA Kamal, MH Khairy, NA ELSadek, MMA Hussein - 2019 - cabidigitallibrary.org
This study attempted to scrutinize the potential efficacy of zinc oxide nanoparticles (ZnONPs)
and the standard oral hypoglycemic drug glibenclamide in streptozotocin (STZ) …

[HTML][HTML] Antidiabetic activity of zinc oxide and silver nanoparticles on streptozotocin-induced diabetic rats

A Alkaladi, AM Abdelazim, M Afifi - International journal of molecular …, 2014 - mdpi.com
The use of nanoparticles in medicine is an attractive proposition. In the present study, zinc
oxide and silver nanoparticles were evaluated for their antidiabetic activity. Fifty male albino …

Zinc oxide nanoparticles show antidiabetic activity in streptozotocin-induced Type 1 and 2 diabetic rats

RD Umrani, KM Paknikar - Nanomedicine, 2014 - Future Medicine
Aim: The correlation of diabetes and an imbalance in zinc homeostasis makes zinc-based
therapy an attractive proposition. In this study, zinc oxide nanoparticles were evaluated for …

Efficacy and safety of combination therapy of zinc and silver oxide nanoparticles in streptozotocin-induced diabetic rats

SS Gaikwad, VP Choudhari - International Journal of Pharmaceutical …, 2022 - ijpras.com
In the present study, Zinc oxide nanoparticles andSilver Oxide nanoparticles were evaluated
for their in vivo and in vitro antidiabetic activity. The resulting ZnO, Ag 2 O were …

Zinc oxide nanoparticles augment CD4, CD8, and GLUT‐4 expression and restrict inflammation response in streptozotocin‐induced diabetic rats

N Elassy, S El‐Dafrawy, AO Abd El‐Azim… - IET …, 2020 - Wiley Online Library
This study evaluated the biochemical, molecular, and histopathological mechanisms
involved in the hypoglycaemic effect of zinc oxide nanoparticles (ZnONPs) in experimental …

Effect of zinc oxide nanoparticles on diabetes development and complications in diabetic rats compared to conventional zinc sulfate and metformin

EE Shaban, ME Abd El-Aziz, KS Ibrahim… - Biocatalysis and …, 2022 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder with numerous secondary complications.
Herein, the effect of zinc oxide-nanoparticles (ZnO-NPs), zinc sulfate-traditional form (ZnSO …

Biological efficacy of zinc oxide nanoparticles against diabetes: a preliminary study conducted in mice

SA Siddiqui, MM Or Rashid, MG Uddin… - Bioscience …, 2020 - portlandpress.com
The antidiabetic, hypoglycemic and oral glucose tolerance test (OGTT) activities of zinc
oxide nanoparticles (ZnONPs) were assessed in mice. ZnONPs were prepared by reacting …

[HTML][HTML] Comparative study of antidiabetic activity and oxidative stress induced by zinc oxide nanoparticles and zinc sulfate in diabetic rats

A Nazarizadeh, S Asri-Rezaie - AAPS PharmSciTech, 2016 - Springer
In the current study, antidiabetic activity and toxic effects of zinc oxide nanoparticles (ZnO)
were investigated in diabetic rats compared to zinc sulfate (ZnSO 4) with particular emphasis …

[HTML][HTML] Zinc oxide nanoparticles induce an adverse effect on blood glucose levels depending on the dose and route of administration in healthy and diabetic rats

A Virgen-Ortiz, A Apolinar-Iribe, I Díaz-Reval… - Nanomaterials, 2020 - mdpi.com
Different studies in experimental diabetes models suggest that zinc oxide nanoparticles
(ZnONPs) are useful as antidiabetic agents. However, this evidence was performed and …