Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links
C de Jorge Martínez, G Rukh, MJ Williams… - Journal of Genetics and …, 2022 - Elsevier
Anorexia nervosa (AN) is a complex disorder with a strong genetic component.
Comorbidities are frequent and there is substantial overlap with other disorders. The lack of …
Comorbidities are frequent and there is substantial overlap with other disorders. The lack of …
Contemporary views on the genetics of anorexia nervosa
PB Shih, DB Woodside - European Neuropsychopharmacology, 2016 - Elsevier
Anorexia nervosa (AN) is a serious mental illness characterized by severe dietary restriction
that leads to high rates of morbidity, chronicity, and mortality. Unfortunately, effective …
that leads to high rates of morbidity, chronicity, and mortality. Unfortunately, effective …
Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
Genetic and epigenetic findings in anorexia nervosa
R Hirtz, A Hinney - Medizinische Genetik, 2020 - degruyter.com
Polygenic factors are relevant for the genetic predispositions to the eating disorder anorexia
nervosa (AN). The most recent genome-wide association study (GWAS) for AN comprised …
nervosa (AN). The most recent genome-wide association study (GWAS) for AN comprised …
[HTML][HTML] The genetics of anorexia nervosa: current findings and future perspectives
AP Pinheiro, T Root, CM Bulik - International journal of child and …, 2009 - ncbi.nlm.nih.gov
Anorexia nervosa is a perplexing illness with the highest mortality rate of any psychiatric
disease. In this paper, we review the genetic research on anorexia nervosa (AN). Family …
disease. In this paper, we review the genetic research on anorexia nervosa (AN). Family …
The genetics of anorexia nervosa
TK Clarke, ARD Weiss… - Clinical Pharmacology & …, 2012 - Wiley Online Library
Anorexia nervosa (AN) is a disease defined by inappropriate weight loss and maintenance
of body weight< 85% of that expected for weight and height; it is most common in adolescent …
of body weight< 85% of that expected for weight and height; it is most common in adolescent …
Genetic findings in anorexia and bulimia nervosa
A Hinney, S Scherag, J Hebebrand - Progress in Molecular Biology and …, 2010 - Elsevier
Anorexia nervosa (AN) and bulimia nervosa (BN) are complex disorders associated with
disordered eating behavior. Heritability estimates derived from twin and family studies are …
disordered eating behavior. Heritability estimates derived from twin and family studies are …
Overview of genetic research in anorexia nervosa: The past, the present and the future
MK Brandys, CGF de Kovel, MJ Kas… - … journal of eating …, 2015 - Wiley Online Library
Background Even though the evidence supporting the presence of a heritable component in
the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain …
the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain …
Bridging the gap: Short structural variants in the genetics of anorexia nervosa
N Berthold, J Pytte, CM Bulik… - … Journal of Eating …, 2022 - Wiley Online Library
Anorexia nervosa (AN) is a devastating disorder with evidence of underexplored heritability.
Twin and family studies estimate heritability (h 2) to be 57%–64%, and genome‐wide …
Twin and family studies estimate heritability (h 2) to be 57%–64%, and genome‐wide …
Association study of 182 candidate genes in anorexia nervosa
AP Pinheiro, CM Bulik, LM Thornton… - American Journal of …, 2010 - Wiley Online Library
We performed association studies with 5,151 SNPs that were judged as likely candidate
genetic variations conferring susceptibility to anorexia nervosa (AN) based on location …
genetic variations conferring susceptibility to anorexia nervosa (AN) based on location …