Higher atrophy rate of entorhinal cortex than hippocampus in AD

AT Du, N Schuff, JH Kramer, S Ganzer, XP Zhu… - Neurology, 2004 - AAN Enterprises
Objectives: To determine if atrophy rates were higher for entorhinal cortex (ERC) than for
hippocampus in Alzheimer disease (AD), to determine the relationship between …

Atrophy rates of entorhinal cortex in AD and normal aging

AT Du, N Schuff, XP Zhu, WJ Jagust, BL Miller… - Neurology, 2003 - AAN Enterprises
Objectives: To explore the atrophy rate of entorhinal cortex (ERC) in AD and normal aging
and assess the value of rate measurement of ERC atrophy for classifying subjects with AD …

MRI measures of entorhinal cortex vs hippocampus in preclinical AD

RJ Killiany, BT Hyman, T Gomez-Isla, MB Moss… - Neurology, 2002 - AAN Enterprises
Background: MRI measures of the entorhinal cortex and the hippocampus have been used
to predict which nondemented individuals with memory problems will progress to meet …

Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD

Y Xu, CR Jack Jr, PC O'Brien, E Kokmen, GE Smith… - Neurology, 2000 - AAN Enterprises
Objective: MRI-based measurements of hippocampal atrophy are a sensitive indicator of the
early pathologic degeneration of the medial temporal lobe in AD. However, AD pathology …

MRI predictors of risk of incident Alzheimer disease: a longitudinal study

TR Stoub, M Bulgakova, S Leurgans, DA Bennett… - Neurology, 2005 - AAN Enterprises
Objective: To determine if baseline entorhinal and hippocampal volumes and their rate of
atrophy could predict the risk of incident Alzheimer disease (AD). Methods: The authors …

Hippocampal atrophy in Alzheimer disease: age matters

LA Van de Pol, A Hensel, F Barkhof, HJ Gertz… - Neurology, 2006 - AAN Enterprises
Hippocampal atrophy is a marker of Alzheimer disease (AD). It remains unclear whether this
holds true for younger patients as well. Hippocampal volume was measured on MRI scans …

Differential aging of the medial temporal lobe: a study of a five-year change

N Raz, KM Rodrigue, D Head, KM Kennedy, JD Acker - Neurology, 2004 - AAN Enterprises
Objective: To test the hypothesis that entorhinal cortex (EC) volume decreases at a slower
rate than the hippocampal (HC) volume in healthy adults, and to examine whether the rate of …

From Healthy Aging to Early Alzheimer's Disease: In Vivo Detection of Entorhinal Cortex Atrophy

L DE TOLEDO‐MORRELL… - Annals of the New …, 2000 - Wiley Online Library
Using quantitative structural MRI protocols, we examined the effects of age on alterations in
entorhinal cortex (EC) volume. The left EC was found to be smaller than the right in both …

Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer's disease

GB Frisoni, MP Laakso, A Beltramello, C Geroldi… - Neurology, 1999 - AAN Enterprises
Objective: To describe atrophic changes of the hippocampus and entorhinal cortex in
frontotemporal dementia (FTD) and compare them with those of AD. Background: The …

Rates of hippocampal atrophy correlate with change in clinical status in aging and AD

CR Jack Jr, RC Petersen, Y Xu, PC O'brien, GE Smith… - Neurology, 2000 - AAN Enterprises
Background: The cognitive continuum in the elderly population can be conceptually divided
into those who are functioning normally (control subjects), those with a mild cognitive …