Obesity and type II diabetes are characterized by insulin resistance in peripheral tissues. A
high caloric intake combined with a sedentary lifestyle is the leading cause of these …

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Obesity is now a worldwide epidemic. In recent years, different phenotypes of obesity,
ranging from metabolically healthy normal weight to metabolically unhealthy obese, were …

Many approaches have been used in the effective management of type 2 diabetes mellitus.
A recent paradigm shift has focused on the role of adipose tissues in the development and …

Obesity is a well-known risk factor for the development of insulin resistance, type 2 diabetes,
dyslipidemia, hypertension, and cardiovascular disease. Rather than the total amount of fat …

The discovery of adipokines has revealed adipose tissue as a central node in the interorgan
crosstalk network, which mediates the regulation of multiple organs and tissues. Adipose …

Adipose tissue is now recognised as a highly active metabolic and endocrine organ. Great
strides have been made in uncovering the multiple functions of the adipocyte in cellular and …

Immoderate energy intake, a sedentary lifestyle, and aging have contributed to the
increased prevalence of obesity, sarcopenia, metabolic syndrome, type 2 diabetes, and …

Skeletal muscle and adipose tissue are the two largest organs in the body. Skeletal muscle
is an effector organ, and adipose tissue is an organ that stores energy; in addition, they are …

Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …