Genetic predisposition to obesity and lifestyle factors–the combined analyses of twenty-six known BMI-and fourteen known waist: hip ratio (WHR)-associated variants …
T Jääskeläinen, J Paananen, J Lindström… - British journal of …, 2013 - cambridge.org
Recent genome-wide association studies have identified multiple loci associated with BMI or
the waist: hip ratio (WHR). However, evidence on gene–lifestyle interactions is still scarce …
the waist: hip ratio (WHR). However, evidence on gene–lifestyle interactions is still scarce …
Gene× dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry
JA Nettleton, JL Follis, JS Ngwa… - Human molecular …, 2015 - academic.oup.com
Obesity is highly heritable. Genetic variants showing robust associations with obesity traits
have been identified through genome-wide association studies. We investigated whether a …
have been identified through genome-wide association studies. We investigated whether a …
Pleiotropic effects of obesity-susceptibility loci on metabolic traits: a meta-analysis of up to 37,874 individuals
JV van Vliet-Ostaptchouk, M den Hoed, J Luan… - Diabetologia, 2013 - Springer
Aims/hypothesis Genetic pleiotropy may contribute to the clustering of obesity and metabolic
conditions. We assessed whether genetic variants that are robustly associated with BMI and …
conditions. We assessed whether genetic variants that are robustly associated with BMI and …
The effect of GWAS identified BMI loci on changes in body weight among middle‐aged Danes during a five‐year period
CH Sandholt, KH Allin, U Toft, A Borglykke… - …, 2014 - Wiley Online Library
Objective Genome‐wide association studies have identified genetic variants associating
with BMI, however, it is un‐clarified whether the same variants also influence body weight …
with BMI, however, it is un‐clarified whether the same variants also influence body weight …
Dietary patterns modify the association between fat mass and obesity-associated genetic variants and changes in obesity phenotypes
F Hosseini-Esfahani, G Koochakpoor… - British journal of …, 2019 - cambridge.org
The present study investigated whether dietary patterns could interact with fat mass and
obesity-associated (FTO) polymorphisms in relation to changes in BMI and waist …
obesity-associated (FTO) polymorphisms in relation to changes in BMI and waist …
Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age
Methods: We examined the association of a genetic risk score (GRS), consisting of 31 BMI-
associated variants, with an annual weight change (AWC) and a substantial weight gain …
associated variants, with an annual weight change (AWC) and a substantial weight gain …
Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study
MD Fesinmeyer, KE North, MD Ritchie, U Lim… - …, 2013 - Wiley Online Library
Objective: Several genome–wide association studies (GWAS) have demonstrated that
common genetic variants contribute to obesity. However, studies of this complex trait have …
common genetic variants contribute to obesity. However, studies of this complex trait have …
Analysis of the interaction between polygenic risk score and calorie intake in obesity in the Korean population
Introduction: Obesity results from an imbalance in the intake and expenditure of calories that
leads to lifestyle-related diseases. Although genome-wide association studies (GWAS) have …
leads to lifestyle-related diseases. Although genome-wide association studies (GWAS) have …
Combined effect of established BMI loci on obesity-related traits in an Algerian population sample
MN Badsi, S Mediene-Benchekor, H Ouhaibi-Djellouli… - BMC genetics, 2014 - Springer
Background Genome-wide association studies have identified variants associated with BMI
in populations of European descent. We sought to establish whether genetic variants that …
in populations of European descent. We sought to establish whether genetic variants that …
Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study
Background We have previously shown that multiple genetic loci identified by genome-wide
association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It …
association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It …