Report of the first international symposium on NUT carcinoma
NUT carcinoma is a rare, aggressive cancer defined by rearrangements of the NUTM1 gene.
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …
[HTML][HTML] NUT carcinoma: clinicopathologic features, molecular genetics and epigenetics
V Moreno, K Saluja, S Pina-Oviedo - Frontiers in Oncology, 2022 - frontiersin.org
Nuclear protein in testis (NUT) carcinoma is a rare, highly aggressive, poorly differentiated
carcinoma occurring mostly in adolescents and young adults. This tumor usually arises from …
carcinoma occurring mostly in adolescents and young adults. This tumor usually arises from …
[HTML][HTML] NUT carcinoma—an underdiagnosed malignancy
UM Lauer, M Hinterleitner, M Horger… - Frontiers in …, 2022 - frontiersin.org
NUT carcinoma (NC) is a rare and highly aggressive malignancy with a dismal prognosis
and a median survival of 6–9 months only. Although very few cases of NC are reported each …
and a median survival of 6–9 months only. Although very few cases of NC are reported each …
NUT Carcinoma: Clinicopathologic features, pathogenesis, and treatment
CA French - Pathology international, 2018 - Wiley Online Library
NUT carcinoma (NC) is a rare, aggressive subtype of squamous cell carcinoma defined by
rearrangement of the NUTM1 (aka NUT) gene. NC is driven by NUT‐fusion oncoproteins …
rearrangement of the NUTM1 (aka NUT) gene. NC is driven by NUT‐fusion oncoproteins …
NUT carcinoma
CA French - Rare Tumors in Children and Adolescents, 2022 - Springer
NUT carcinoma (NC) is defined molecularly by rearrangement of the NUTM1 gene and is
most commonly driven by the BRD4-NUT oncoprotein. Patients are typically in their teens or …
most commonly driven by the BRD4-NUT oncoprotein. Patients are typically in their teens or …
[HTML][HTML] An overview of molecular mechanism, clinicopathological factors, and treatment in NUT carcinoma
QW Huang, LJ He, S Zheng, T Liu… - BioMed Research …, 2019 - hindawi.com
NUT carcinoma (NC) is a rare and poorly differentiated tumor, with highly aggressive and
fatal neoplasm. NC is characterized by chromosomal rearrangement involving NUTM1 …
fatal neoplasm. NC is characterized by chromosomal rearrangement involving NUTM1 …
[HTML][HTML] Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma—An aggressive and fatal disease
A Stirnweiss, J Oommen, RS Kotecha, UR Kees… - Oncotarget, 2017 - ncbi.nlm.nih.gov
NUT midline carcinoma (NMC) is a rare and aggressive cancer, with survival typically less
than seven months, that can arise in people of any age. Genetically, NMC is defined by the …
than seven months, that can arise in people of any age. Genetically, NMC is defined by the …
Clinicopathological and preclinical findings of NUT carcinoma: a multicenter study
M Jung, S Kim, JK Lee, SO Yoon, HS Park… - The …, 2019 - academic.oup.com
Background NUT carcinoma is a rare aggressive disease caused by BRD4/3‐NUT fusion,
and C‐MYC upregulation plays a key role in the pathogenesis. Here, we report on the …
and C‐MYC upregulation plays a key role in the pathogenesis. Here, we report on the …
NUT midline carcinoma
C French - Nature Reviews Cancer, 2014 - nature.com
NUT midline carcinoma, a squamous cell carcinoma, is one of the most aggressive human
cancers, and there is a desperate need for effective therapies for patients with this disease …
cancers, and there is a desperate need for effective therapies for patients with this disease …
Novel BRD4–NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma
K Thompson-Wicking, RW Francis, A Stirnweiss… - Oncogene, 2013 - nature.com
Nuclear protein in testis (NUT)-midline carcinoma (NMC) is a rare, aggressive disease
typically presenting with a single t (15; 19) translocation that results in the generation of a …
typically presenting with a single t (15; 19) translocation that results in the generation of a …