Preimplantation embryology: The molecular genetics of the zona pellucida: mouse mutations and infertility

T Rankin, J Dean - MHR: Basic science of reproductive …, 1996 - academic.oup.com
The zona pellucida is an extracellular matrix surrounding growing oocytes, ovulated eggs
and the preimplantation embryo. After mediating the relatively species-specific events of …

[HTML][HTML] Zona pellucida genes and proteins and human fertility

ES Litscher, PM Wassarman - Trends in developmental biology, 2020 - ncbi.nlm.nih.gov
The zona pellucida (ZP) is an extracellular matrix (ECM) that surrounds all mammalian
oocytes, eggs, and embryos and plays vital roles during oogenesis, fertilization, and …

Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development

TL Rankin, M O'Brien, E Lee, K Wigglesworth… - …, 2001 - journals.biologists.com
All vertebrate eggs are surrounded by an extracellular matrix. This matrix is known as the
zona pellucida in mammals and is critically important for the survival of growing oocytes …

Coordinate expression of the three zona pellucida genes during mouse oogenesis

O Epifano, L Liang, M Familari, MC Moos Jr… - …, 1995 - journals.biologists.com
The mammalian zona pellucida is an extracellular matrix that surrounds growing oocytes,
ovulated eggs and early embryos. The mouse zona is composed of three sulfated …

Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins

RD Lunsford, NA Jenkins, CA Kozak, L Liang, CM Silan… - Genomics, 1990 - Elsevier
The zona pellucida is a unique, oocyte-specific matrix that coats the surface of all
mammalian eggs. Composed of three sulfated glycoproteins in the mouse (ZP1, ZP2, and …

Mutant Zp1 impedes incorporation of ZP3 and ZP4 in the zona pellucida, resulting in zona absence and female infertility in rats

C Lv, HL Huang, DJ Yi, TL Peng, HJ Tan… - Biology of …, 2021 - academic.oup.com
The zona pellucida (ZP) plays vital roles in reproductive processes including oogenesis,
fertilization, and preimplantation development. Both human and rat ZP consist of four …

The mouse zona pellucida: folliculogenesis, fertility and pre-implantation development

T Rankin, S Soyal, J Dean - Molecular and cellular endocrinology, 2000 - Elsevier
Perinatally, oocytes within the mouse ovary become surrounded by a layer of flattened
granulosa cells and form primordial follicles. The subsequent accretion of the zona pellucida …

Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile

T Rankin, M Familari, E Lee, A Ginsberg… - …, 1996 - journals.biologists.com
Mammalian oocytes synthesize and secrete a zona pellucida that surrounds the growing
oocytes, ovulated eggs and preimplantation embryos. The extracellular zona matrix is …

[HTML][HTML] Zona pellucida genes and proteins: Essential players in mammalian oogenesis and fertility

PM Wassarman, ES Litscher - Genes, 2021 - mdpi.com
All mammalian oocytes and eggs are surrounded by a relatively thick extracellular matrix
(ECM), the zona pellucida (ZP), that plays vital roles during oogenesis, fertilization, and …

ZP4 confers structural properties to the zona pellucida essential for embryo development

I Lamas-Toranzo, N Fonseca Balvis… - Elife, 2019 - elifesciences.org
Zona pellucida (ZP), the extracellular matrix sheltering mammalian oocytes and embryos, is
composed by 3 to 4 proteins. The roles of the three proteins present in mice have been …