Vitamin D and its' metabolites are a crucial part of the endocrine system that controls whole
body calcium homeostasis. The goal of this hormonal control is to regulate serum calcium …

Vitamin D is one of the oldest hormones that have been made in the earliest life forms for
over 750 million years. Phytoplankton, zooplankton, and most plants and animals that are …

A history of vitamin D has been provided, dating from the earliest description of rickets, the
disease resulting from vitamin D deficiency, to a current understanding of vitamin D …

The hormonal metabolite of vitamin D, 1α, 25-dihydroxyvitamin D 3 (1, 25D), initiates
biological responses via binding to the vitamin D receptor (VDR). When occupied by 1, 25D …

Publisher Summary Vitamin D is one of the major regulators of calcium homeostasis in the
body and is critically important for normal mineralization of bone. The active hormone, 1α, 25 …

The endocrine action of plasma 1, 25-dihydroxyvitamin D plays a key role in the regulation
of plasma calcium and phosphate homeostasis with activities on the intestine, kidney and …

The vitamin D endocrine system plays a primary role in the maintenance of calcium
homeostasis as well as exerting a wider range of biological activities including the …

Vitamin D is the major regulator of calcium homeostasis and protects the organism from
calcium deficiency via effects on the intestine, kidney, parathyroid gland, and bone …

Vitamin D plays a major role in bone mineral homeostasis by promoting the transport of
calcium and phosphate to ensure that the blood levels of these ions are sufficient for the …

Publisher Summary Vitamin D 3 is photobiosynthesized in the epidermis from 7-dehydro-
cholesterol, a normal byproduct of cholesterol synthesis. As it can be generated in the body …