Heat shock RNA levels in brain and other tissues after hyperthermia and transient ischemia

TS Nowak Jr, U Bond… - Journal of …, 1990 - Wiley Online Library
A number of studies have demonstrated increased synthesis of heat shock proteins in brain
following hyperthermia or transient ischemia. In the present experiments we have …

Induction of heat shock (stress) genes in the mammalian brain by hyperthermia and other traumatic events: a current perspective

IR Brown - Journal of neuroscience research, 1990 - Wiley Online Library
Is the heat shock response physiologically relevant? For example, following hyperthermia or
ischemia, what neural cell types show induction of heat shock genes and what is the time …

Localization of 70 kDa stress protein mRNA induction in gerbil brain after ischemia

TS Nowak Jr - Journal of Cerebral Blood Flow & Metabolism, 1991 - journals.sagepub.com
Induction of mRNA encoding the 70 kDa stress/heat shock protein, hsp70, was evaluated in
postischemic gerbil brain by in situ hybridization using an oligonucleotide probe selective for …

Expression of heat shock genes (hsp70) in the mammalian brain: Distinguishing constitutively expressed and hyperthermia‐inducible mRNA species

IR Brown, SJ Rush - Journal of neuroscience research, 1990 - Wiley Online Library
The mammalian genome contains both constitutively expressed and heat‐shock‐inducible
members of the hsp70 gene family. Riboprobes derived from members of these two classes …

The heat shock stress response after brain lesions: induction of 72 kDa heat shock protein (cell types involved, axonal transport, transcriptional regulation) and protein …

AM Planas, MA Soriano, A Estrada, O Sanz… - Progress in …, 1997 - Elsevier
The cerebral stress response is examined following a variety of pathological conditions such
as focal and global ischemia, administration of excitotoxins, and hyperthermia. Expression of …

Differential induction of heat shock mRNA in oligodendrocytes, microglia, and astrocytes following hyperthermia

JA Foster, IR Brown - Molecular Brain Research, 1997 - Elsevier
A time course analysis of hsp70 mRNA induction in response to a physiologically relevant
increase in body temperature of 2.6° C was performed in the rabbit forebrain. A protocol that …

Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat

H Kinouchi, FR Sharp, MP Hill… - Journal of Cerebral …, 1993 - journals.sagepub.com
Induction of the 70-kDa heat shock protein (HSP70) was demonstrated
immunocytochemically in adult rats 4 h to 7 days following temporary middle cerebral artery …

Expression of heat shock genes (hsp70) in the rabbit spinal cord: Localization of constitutive and hyperthermia‐inducible mRNA species

P Manzerra, IR Brown - Journal of neuroscience research, 1992 - Wiley Online Library
We have previously reported that hyperthermia induces the expression of a heat shock gene
in the rabbit brain (Sprang and Brown, Mol Brain Res 3: 89–93, 1987). Striking regional and …

Localization of 70-kDa stress protein induction in gerbil brain after ischemia

K Vass, WJ Welch, TS Nowak - Acta neuropathologica, 1988 - Springer
Induction of the 70-kDa heat shock protein, hsp70, has been demonstrated in brain following
experimental stroke. In the present study, hsp70 was localized in gerbil brain at intervals …

Temporal and spatial distribution of heat shock mRNA and protein (hsp70) in the rabbit cerebellum in response to hyperthermia

P Manzerra, SJ Rush, IR Brown - Journal of neuroscience …, 1993 - Wiley Online Library
We have previously investigated the expression of hsp70 genes in the hyperthermic rabbit
brain at the mRNA level by Northern blot and in situ hybridization procedures. Our studies …