Purpose We aimed to identify pathogenic variants in two infertile sisters in a family with a
thin zona pellucida (ZP) phenotype. Methods Whole-exome sequencing was performed in …

Zona pellucida (ZP) which is an extracellular matrix consisting of ZP1, ZP2, ZP3, and ZP4
plays a vital role in oocyte maturity, early embryonic development, and fertilization process …

The human zona pellucida (ZP) is an extracellular glycoprotein matrix composed of ZP1,
ZP2, ZP3, and ZP4 surrounding the oocyte, and it plays an important role in sperm–egg …

Background The zona pellucida (ZP) of human oocytes plays essential protective roles in
sperm–egg interactions during fertilisation and embryo development. ZP4-null female …

Introduction Human zona pellucida (ZP) plays an important role in reproductive process.
Several rare mutations in the encoding genes (ZP1, ZP2, and ZP3) have been demonstrated …

The zona pellucida (ZP) plays vital roles in reproductive processes including oogenesis,
fertilization, and preimplantation development. Both human and rat ZP consist of four …

The human zona pellucida (ZP) is a highly organized glycoprotein matrix that encircles
oocytes and plays an essential role in successful reproduction. Previous studies have …

The human zona pellucida is composed of four glycoproteins (ZP1, ZP2, ZP3, and ZP4) and
has an important role in reproduction. Here we describe a form of infertility with an …

The zona pellucida (ZP) is an extracellular glycoprotein matrix surrounding mammalian
oocytes. Recently, numerous mutations in genes encoding ZP proteins have been shown to …

OBJECTIVE: To investigate genetic, molecular and functional aspects of human zona
pellucida (ZP) in oocytes with an abnormal appearance. STUDY DESIGN: The study …