Remote ischemic conditioning preserves cognition and motor coordination in a mouse model of traumatic brain injury

AJ Sandweiss, A Azim, K Ibraheem… - Journal of Trauma …, 2017 - journals.lww.com
METHODS We subjected 100 male C57BL mice to a closed-skull cortical-controlled impact
injury. Two hours after the TBI, the animals were allocated to either the RIC group (n= 50) or …

Continuous remote ischemic conditioning attenuates cognitive and motor deficits from moderate traumatic brain injury

V Pandit, M Khan, TM Largent-Milnes… - Journal of Trauma …, 2018 - journals.lww.com
BACKGROUND While studies show that single-dose remote ischemic conditioning (RIC)
improves outcomes, the effect of continuous (daily) RIC is unknown. Thus, we aimed to …

Secondary brain injury in trauma patients: the effects of remote ischemic conditioning

B Joseph, V Pandit, B Zangbar… - Journal of Trauma …, 2015 - journals.lww.com
BACKGROUND Management of traumatic brain injury (TBI) is focused on preventing
secondary brain injury. Remote ischemic conditioning (RIC) is an established treatment …

Per-and post-remote ischemic conditioning attenuates ischemic brain injury via inhibition of the TLR4/MyD88 signaling pathway in aged rats

J Lv, W Yan, J Zhou, H Pei, R Zhao - Experimental Brain Research, 2021 - Springer
Remote ischemic conditioning (RIC), as an emerging protective method, might be used
clinically to prevent ischemia–reperfusion injury (IRI) in ischemic stroke. In this study, we aim …

Remote ischemic post-conditioning reduced brain damage in experimental ischemia/reperfusion injury

C Ren, M Gao, D Dornbos, Y Ding, X Zeng… - Neurological …, 2011 - Taylor & Francis
Objectives: To determine the protective effects of remote post-conditioning on ischemic brain
lesions caused by middle cerebral artery (MCA) occlusion in rats. Methods: A total of 54 …

Neuroprotection by remote ischemic conditioning in the setting of acute ischemic stroke: a preclinical two-centre study

MV Basalay, M Wiart, F Chauveau, C Dumot, C Leon… - Scientific Reports, 2020 - nature.com
Reperfusion is the only existing strategy for patients with acute ischemic stroke, however it
causes further brain damage itself. A feasible therapy targeting reperfusion injury is remote …

A feasible strategy for focal cerebral ischemia-reperfusion injury: remote ischemic postconditioning

Q Liu, S Zhou, Y Wang, F Qi, Y Song… - Neural Regeneration …, 2014 - journals.lww.com
It is difficult to control the degree of ischemic postconditioning in the brain and other
ischemia-sensitive organs. Remote ischemic postconditioning could protect some ischemia …

The changes of systemic immune responses during the neuroprotection induced by remote ischemic postconditioning against focal cerebral ischemia in mice

C Liu, J Yang, C Zhang, X Geng, H Zhao - Neurological Research, 2019 - Taylor & Francis
Objective: Remote limb ischemic postconditioning (RIPostC) protects the brain from damage
induced by transient focal ischemia/reperfusion. However, the underlying mechanism …

Effect of remote ischemic postconditioning on an intracerebral hemorrhage stroke model in rats

X Geng, C Ren, T Wang, P Fu, Y Luo, X Liu… - Neurological …, 2012 - Taylor & Francis
Background and purpose: While recent studies suggest that remote ischemic
postconditioning (RIP) therapy may be of benefit to patients with acute ischemic stroke, RIP's …

Remote ischemic postconditioning protects the brain from focal ischemia/reperfusion injury by inhibiting autophagy through the mTOR/p70S6K pathway

G Chen, X Shan, X Li, H Tao - Neurological research, 2018 - Taylor & Francis
Abstract Objective: Remote ischemic postconditioning (RIPostC) has been recognized as an
applicable strategy for protecting against cerebral ischemia/reperfusion (I/R) injury. This …