Direct effects of an opioid peptide selective for μ-receptors: intracellular recordings in the paraventricular and supraoptic nuclei of the guinea-pig

JP Wuarin, FE Dudek - Neuroscience, 1990 - Elsevier
Abstract Responses to [d-Ala 2, MePhe 4, Gly-ol 5] enkephalin, a selective agonist for μ-
receptors, were recorded intracellularly from 26 neurons in slices of guinea-pig …

Effect of opioid peptides on the paraventricular nucleus of the guinea pig hypothalamus is mediated by μ-type receptors

JP Wuarin, M Dubois-Dauphin, M Raggenbass… - Brain research, 1988 - Elsevier
The effects of opioid peptides on paraventricular neurons were investigatedby using
intracellular recordings from hypothalamic slices of the guinea pig. Forty-eight out of 128 …

μ-Opioid peptides inhibit thalamic neurons

J Brunton, S Charpak - Journal of Neuroscience, 1998 - Soc Neuroscience
Opioidergic inhibition of neurons in the centrolateral nucleus of the thalamus was
investigated using an in vitro thalamic slice preparation from young rats. The μ-opioid …

Direct inhibition by opioid peptides of neurones located in the ventromedial nucleus of the guinea pig hypothalamus

S Charpak, M Dubois-Dauphin, M Raggenbass… - Brain research, 1988 - Elsevier
In slices of guinea pig brain, intracellular recordings were obtained from neurones of the
ventromedial nucleus of the hypothalamus (VMH).[d-Ala 2, NMePhe 4, Gly-ol 5] enkephalin …

Membrane Properties of Identified Guinea‐Pig Paraventricular Neurons and their Response to an Opioid μ‐Receptor Agonist: Evidence for an Increase in K+ …

M Kasai, JG Tasker, JP Wuarin… - Journal of …, 1993 - Wiley Online Library
Intracellular recordings were obtained from neurons in the paraventricular nucleus (PVN) of
guinea‐pig hypothalamic slices. Passive and active properties of the neurons were …

Opioids act at μ-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance

MD Loose, MJ Kelly - Brain research, 1990 - Elsevier
Intracellular recordings were made from 48 hypothalamic arcuate (ARC) neurons under
current-and voltage-clamp in slices prepared from female guinea pigs which had been …

µ‐Opioid Receptor Modulates Peptide Release From Rat Neurohypophysial Terminals By Inhibiting Ca2+ Influx

SI Ortiz‐Miranda, G Dayanithi, V Coccia… - Journal of …, 2003 - Wiley Online Library
The activation of opioid receptors in neurones of the central nervous system leads to a
variety of effects including the modulation of diuresis and parturition, processes that are …

Opioid peptides selective for mu-and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance

MA Werz, RL Macdonald - Neuroscience letters, 1983 - Elsevier
We suggest that both mu-and delta-opiate receptors on dorsal root ganglion neuron somata
are coupled to voltage-and/or calcium-dependent potassium channels since opioid peptide …

Differential modulation of N‐type calcium channels by µ‐opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals

SI Ortiz‐Miranda, G Dayanithi… - Journal of cellular …, 2010 - Wiley Online Library
Opioids modulate the electrical activity of magnocellular neurons (MCN) and inhibit
neuropeptide release at their terminals in the neurohypophysis. We have previously shown …

Kappa‐selective opioid receptor agonists leumorphin and dynorphin inhibit supraoptic neurons in rat hypothalamic slice preparations

K Inenaga, H Imura, N Yanaihara… - Journal of …, 1990 - Wiley Online Library
To clarify the effects of opioid peptides, and in particular the effects of kappa‐receptor
agonists on the activity of supraoptic neurons, extracellular recordings were made from 71 …