The antitumor and antimetastatic activities of the plant cysteine endoproteinase bromelaine
were evaluated in a murine model. Syngeneic sarcoma L-1 cells were incubated with …

Our recent studies, in vitro, with bromelain, a natural product, indicated specific retardation of
Lewis lung carcinoma, YC-8 lymphoma, and MCA-1 ascitic tumor cells (1) as well as a …

Abstract Stem bromelain (EC 3.4. 22.32) is a major cysteine proteinase, isolated from
pineapple (Ananas comosus) stem. Its main medicinal use is recognized as digestive, in …

Bromelain, a pineapple-derived plant product, added to C57B1/6 mice laboratory chow
decreased lung metastasis of Lewis lung cancer cells implanted sc This antimetastatic …

Recent reports have shown that bromelain (BL), a pineapple extract, acts as an adjuvant
therapy in cancer treatment and prevention of carcinogenesis. The present study was …

Background Bromelain is a pineapple stem extract with a variety of therapeutic benefits
arising from interaction with a number of different biological processes. Several preclinical …

The medicinal qualities of pineapple are recognized in many traditions in South America,
China and Southeast Asia. These qualities are attributed to bromelain, a 95%-mixture of …

Bromelain is an aqueous extract from pineapple stem that contains proteinases and exhibits
pleiotropic therapeutic effects, ie, antiedematous, antiinflammatory, antimetastatic …

Purpose Poor efficacy of conventional chemotherapeutic drugs against metastatic hormone-
refractory prostate cancer (CaP) drives patients to try" alternative medicine". The antitumor …

Non steroidal anti-inflammatory drugs such as aspirin and indomethacin associated with
inhibition of platelet aggregation (1, 2, 3) have been reported to retard tumour growth (4) …