Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum
Y Kubohara, H Kikuchi, VH Nguyen… - Biology …, 2017 - journals.biologists.com
ABSTRACT Differentiation-inducing factor-1 [1-(3, 5-dichloro-2, 6-dihydroxy-4-
methoxyphenyl) hexan-1-one (DIF-1)] is an important regulator of cell differentiation and …
methoxyphenyl) hexan-1-one (DIF-1)] is an important regulator of cell differentiation and …
Artificial compounds differentially control Dictyostelium chemotaxis and cell differentiation
H Kuwayama, H Kikuchi, Y Oshima… - Cell structure and …, 2011 - jstage.jst.go.jp
Differentiation-inducing factor-1 and-2 (DIF-1 and DIF-2) are small lipophilic signal
molecules that control both cell differentiation and chemotaxis in the cellular slime mold …
molecules that control both cell differentiation and chemotaxis in the cellular slime mold …
[HTML][HTML] Derivatives of Differentiation-Inducing Factor 1 Differentially Control Chemotaxis and Stalk Cell Differentiation in Dictyostelium discoideum
H Kuwayama, H Kikuchi, Y Kubohara - Biology, 2023 - mdpi.com
Simple Summary In this study, we examined the effects of nine DIF derivatives on
chemotactic cell movement toward cAMP and compared their chemotaxis-modulating …
chemotactic cell movement toward cAMP and compared their chemotaxis-modulating …
[HTML][HTML] Glutathione S-transferase 4 is a putative DIF-binding protein that regulates the size of fruiting bodies in Dictyostelium discoideum
H Kuwayama, H Kikuchi, Y Oshima… - … and Biophysics Reports, 2016 - Elsevier
In the development of the cellular slime mold Dictyostelium discoideum, two chlorinated
compounds, the differentiation-inducing factors DIF-1 and DIF-2, play important roles in the …
compounds, the differentiation-inducing factors DIF-1 and DIF-2, play important roles in the …
[HTML][HTML] Differentiation-Inducing Factor-1 and -2 Function also as Modulators for Dictyostelium Chemotaxis
H Kuwayama, Y Kubohara - PLoS One, 2009 - journals.plos.org
Background In the early stages of development of the cellular slime mold Dictyostelium
discoideum, chemotaxis toward cAMP plays a pivotal role in organizing discrete cells into a …
discoideum, chemotaxis toward cAMP plays a pivotal role in organizing discrete cells into a …
Preparation of an antibody that recognizes and neutralizes Dictyostelium differentiation-inducing factor-1
Y Kubohara, H Kikuchi, K Nakamura, Y Matsuo… - Biochemical and …, 2010 - Elsevier
In the development of the cellular slime mold Dictyostelium discoideum, the differentiation-
inducing factor-1 (DIF-1; 1-(3, 5-dichloro-2, 6-dihydroxy-4-methoxyphenyl) hexan-1-one) …
inducing factor-1 (DIF-1; 1-(3, 5-dichloro-2, 6-dihydroxy-4-methoxyphenyl) hexan-1-one) …
Differentiation‐inducing factor 2 modulates chemotaxis via the histidine kinase DhkC‐dependent pathway in Dictyostelium discoideum
H Kuwayama, Y Kubohara - FEBS letters, 2016 - Wiley Online Library
Differentiation‐inducing factor 1 (DIF‐1) and DIF‐2 are signaling molecules that control
chemotaxis in Dictyostelium discoideum. Whereas DIF‐1 suppresses chemotaxis in shallow …
chemotaxis in Dictyostelium discoideum. Whereas DIF‐1 suppresses chemotaxis in shallow …
[HTML][HTML] Involvement of GSK-3β and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells
F Takahashi-Yanaga, J Mori, E Matsuzaki… - Journal of biological …, 2006 - ASBMB
Differentiation-inducing factors (DIFs) are putative morphogens that induce cell
differentiation in Dictyostelium discoideum. We previously reported that DIF-3 activates …
differentiation in Dictyostelium discoideum. We previously reported that DIF-3 activates …
[HTML][HTML] Inhibiting Neddylation with MLN4924 Suppresses Growth and Delays Multicellular Development in Dictyostelium discoideum
Neddylation is a post-translational modification that is essential for a variety of cellular
processes and is linked to many human diseases including cancer, neurodegeneration, and …
processes and is linked to many human diseases including cancer, neurodegeneration, and …
Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum
Y Kubohara, H Kikuchi, Y Matsuo, Y Oshima… - Biology …, 2014 - journals.biologists.com
ABSTRACT Differentiation-inducing factor-3 (DIF-3), found in the cellular slime mold
Dictyostelium discoideum, and its derivatives, such as butoxy-DIF-3 (Bu-DIF-3), are potent …
Dictyostelium discoideum, and its derivatives, such as butoxy-DIF-3 (Bu-DIF-3), are potent …