The perception of visceral pain is a complex process involving the spinal cord and higher
order brain structures. Increasing evidence implicates the gut microbiota as a key regulator …

The impact of the gut microbiota on glial cell growth and maturation via the gut-brain axis is
highlighted herein. Considering that glial activation is crucial for onset and maintenance of …

A complex set of interactions between the microbiome, gut and brain modulate responses to
visceral pain. These interactions occur at the level of the gastrointestinal mucosa, and via …

Background Visceral pain is a complex and heterogeneous disorder, which can range from
the mild discomfort of indigestion to the agonizing pain of renal colic. Regulation of visceral …

Abdominal pain is common in patients with gastrointestinal disorders, but its
pathophysiology is unclear, in part due to poor understanding of basic mechanisms …

BACKGROUND: Gut microbiota, a consortium of diverse microorganisms residing in the
gastrointestinal tract, has emerged as a key player in neuroinflammatory responses …

Among the various regulators of the nervous system, the gut microbiota has been recently
described to have the potential to modulate neuronal cells activation. While bacteria-derived …

Disruption of bacterial colonization during the early postnatal period is increasingly being
linked to adverse health outcomes. Indeed, there is a growing appreciation that the gut …

The ability of an individual to sense pain is fundamental for its capacity to adapt to its
environment and to avoid damage. The sensation of pain can be enhanced by acute or …

Background Stress leads to altered gastrointestinal neuro‐immune responses. We
characterized the interaction between stress and gut commensal microbiota and their role …