P14ARF sensitizes human osteosarcoma cells to cisplatin-induced apoptosis in a p53-independent manner
XW Yuan, XF Zhu, XF Huang, PY Sheng… - Cancer Biology & …, 2007 - Taylor & Francis
The tumor suppressor p14ARF, encoded by the INK4a/ARF locus, is often disrupted in
human cancers. p14ARF triggers cell cycle arrest and sensitizes cells to apoptosis in the …
human cancers. p14ARF triggers cell cycle arrest and sensitizes cells to apoptosis in the …
Recombinant adenovirus-mediated p14ARF overexpression sensitizes human breast cancer cells to cisplatin
X Deng, M Kim, D Vandier, Y Jung, T Rikiyama… - Biochemical and …, 2002 - Elsevier
p14ARF, the alternative product from the human INK4a/ARF locus, is one of the major
targets for alterations in the development of human cancers. Overexpression of p14ARF …
targets for alterations in the development of human cancers. Overexpression of p14ARF …
p14ARF enhances cisplatin-induced apoptosis in human osteosarcoma cells in p53-independent pathway
X Huang, X Yuan, Z Chen, S Liang - Zhonghua yi xue za zhi, 2015 - europepmc.org
Objective To study effect of tumor suppressor p14ARF on cisplatin-induced apoptosis in
human osteosarcoma cells with its molecular mechanisms to provide evidences for …
human osteosarcoma cells with its molecular mechanisms to provide evidences for …
Enforced expression of p14ARF induces p53-dependent cell cycle arrest but not apoptosis
Expression of the p14ARF tumour suppressor is induced by hyperproliferative signals
produced by RAS, MYC and other oncogenes. p14ARF quenches inappropriate mitogenic …
produced by RAS, MYC and other oncogenes. p14ARF quenches inappropriate mitogenic …
Adenovirus-mediated overexpression of p14ARF induces p53 and Bax-independent apoptosis
PG Hemmati, B Gillissen, C von Haefen, J Wendt… - Oncogene, 2002 - nature.com
The human INK4a gene locus encodes two structurally unrelated tumor suppressor proteins,
p16 INK4a and p14 ARF, which are frequently inactivated in human cancer. Whereas p16 …
p16 INK4a and p14 ARF, which are frequently inactivated in human cancer. Whereas p16 …
Apoptosis induced by adenovirus-mediated p14ARF expression in U2OS osteosarcoma cells is associated with increased Fas expression
M Kim, M Sgagias, X Deng, YJ Jung, T Rikiyama… - Biochemical and …, 2004 - Elsevier
The INK4A/ARF locus on chromosome 9 is a tumor suppressor gene frequently mutated in
human cancers. In order to study the effects of p14ARF expression in tumor cells, we …
human cancers. In order to study the effects of p14ARF expression in tumor cells, we …
Human p14ARF-mediated cell cycle arrest strictly depends on intact p53 signaling pathways
HO Weber, T Samuel, P Rauch, JO Funk - Oncogene, 2002 - nature.com
The tumor suppressor ARF is transcribed from the INK4a/ARF locus in partly overlapping
reading frames with the CDK inhibitor p16 Ink4a. ARF is able to antagonize the MDM2 …
reading frames with the CDK inhibitor p16 Ink4a. ARF is able to antagonize the MDM2 …
P14ARF: The Absence that Makes the Difference
D Cilluffo, V Barra, A Di Leonardo - Genes, 2020 - mdpi.com
P14ARF is a tumor suppressor encoded by the CDKN2a locus that is frequently inactivated
in human tumors. P14ARF protein quenches oncogene stimuli by inhibiting cell cycle …
in human tumors. P14ARF protein quenches oncogene stimuli by inhibiting cell cycle …
Arf induces p53-dependent and-independent antiproliferative genes
ML Kuo, EJ Duncavage, R Mathew, W Den Besten… - Cancer Research, 2003 - AACR
The tumor suppressor p19Arf (p14ARF in humans), encoded by the Ink4a/Arf locus, is
mutated, deleted, or silenced in many forms of cancer. p19Arf induces growth arrest by …
mutated, deleted, or silenced in many forms of cancer. p19Arf induces growth arrest by …
Loss of p21 disrupts p14ARF-induced G1 cell cycle arrest but augments p14ARF-induced apoptosis in human carcinoma cells
PG Hemmati, G Normand, B Verdoodt, C von Haefen… - Oncogene, 2005 - nature.com
The human INK4a locus encodes two structurally unrelated tumor suppressor proteins, p16
INK4a and p14 ARF (p19 ARF in the mouse), which are frequently inactivated in human …
INK4a and p14 ARF (p19 ARF in the mouse), which are frequently inactivated in human …