Antivirus immune activity in multiple sclerosis correlates with MRI activity

LB Latham, MJ Lee, JA Lincoln, N Ji… - Acta Neurologica …, 2016 - Wiley Online Library
Objective The objective of this study was to determine whether reactivation of Epstein‐Barr
(EBV) or activation of the anti‐EBV immune response correlates with MS disease activity on …

Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI

RA Farrell, D Antony, GR Wall, DA Clark, L Fisniku… - Neurology, 2009 - AAN Enterprises
Background: Evidence suggests that Epstein-Barr virus (EBV) plays a role in triggering or
perpetuating disease activity in multiple sclerosis (MS). Methods: We investigated 100 …

Epstein-Barr virus and disease activity in multiple sclerosis

D Buljevac, GJJ Van Doornum, HZ Flach… - Journal of Neurology …, 2005 - jnnp.bmj.com
Objectives: To study in relapsing–remitting (RR) multiple sclerosis (MS) whether
exacerbations and brain activity as measured by magnetic resonance imaging (MRI) are …

Immune and Epstein-Barr virus gene expression in cerebrospinal fluid and peripheral blood mononuclear cells from patients with relapsing-remitting multiple sclerosis

C Veroni, F Marnetto, L Granieri, A Bertolotto… - Journal of …, 2015 - Springer
Background Gene expression analyses in paired cerebrospinal fluid (CSF) and peripheral
blood mononuclear cells (PBMC) from patients with multiple sclerosis (MS) are restrained by …

Interferon beta results in immediate reduction of contrast‐enhanced MRI lesions in multiple sclerosis patients followed by weekly MRI

PA Calabresi, LA Stone, CN Bash, JA Frank… - Neurology, 1997 - AAN Enterprises
Interferon beta-la and-1b reduce the frequency and severity of clinical exacerbations, and
reduce both T,-weighted and contrast-enhanced MRI activity in patients with multiple …

Antibodies to Epstein-Barr virus and MRI disease activity in multiple sclerosis

S Kvistad, KM Myhr, T Holmøy, S Bakke… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Previous reports indicate an association between Epstein-Barr virus (EBV)
antibody levels and multiple sclerosis (MS) disease activity, but the results have been …

Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis

RM Gieß, C Pfuhl, JR Behrens, L Rasche, E Freitag… - PloS one, 2017 - journals.plos.org
Objective To investigate the association of Epstein-Barr virus (EBV) nuclear antigen-1
(EBNA-1) and viral capsid antigen (VCA) immunoglobulin (Ig) G antibodies in serum as well …

An altered immune response to Epstein-Barr virus in multiple sclerosis: a prospective study

P Sundstrom, P Juto, G Wadell, G Hallmans… - Neurology, 2004 - AAN Enterprises
Objective: To investigate the association between human herpesviruses and multiple
sclerosis (MS), as well as between measles virus and MS. Methods: The authors identified …

Epstein–Barr virus reactivation and multiple sclerosis

Ø Torkildsen, H Nyland, H Myrmel… - European journal of …, 2008 - Wiley Online Library
Infection with Epstein–Barr virus (EBV) is considered one of the possible key environmental
factors in the aetiology of multiple sclerosis (MS). Whether EBV plays an underlying role as …

The risk of relapses in multiple sclerosis during systemic infections

J Correale, M Fiol, W Gilmore - Neurology, 2006 - AAN Enterprises
Objectives: To assess the risk of multiple sclerosis (MS) relapses, MRI activity, and T cell
responses during systemic infections (SI) in patients with MS. Methods: The authors …