Dopaminergic modulation of brain systems subserving decision making under uncertainty: a study with fMRI and methylphenidate challenge

RGM Schlösser, I Nenadic, G Wagner, S Zysset… - Synapse, 2009 - Wiley Online Library
There is evidence that the dopaminergic system is involved in probabilistic reinforcement
learning and reward‐related decision‐making. However, little is known about the effects of …

Prefrontal, parietal, and temporal cortex networks underlie decision-making in the presence of uncertainty

MP Paulus, N Hozack, B Zauscher, JE McDowell… - Neuroimage, 2001 - Elsevier
Decision-making in the presence of uncertainty, ie, selecting a sequence of responses in an
uncertain environment according to a self-generated plan of action, is a complex activity that …

Brain areas activated by uncertain reward-based decision-making in healthy volunteers

Z Guo, J Chen, S Liu, Y Li, B Sun… - Neural regeneration …, 2013 - journals.lww.com
Reward-based decision-making has been found to activate several brain areas, including
the ventrolateral prefrontal lobe, orbitofrontal cortex, anterior cingulate cortex, ventral …

Investigation of decision-making under uncertainty in healthy subjects: A multi-centric fMRI study

A Krug, M Cabanis, M Pyka, K Pauly, H Walter… - Behavioural brain …, 2014 - Elsevier
Decision-making is an everyday routine that entails several subprocesses. Decisions under
uncertainty occur when either prior information is incomplete or the outcomes of the decision …

The uncertain brain: A co-ordinate based meta-analysis of the neural signatures supporting uncertainty during different contexts

J Morriss, M Gell, CM van Reekum - Neuroscience & Biobehavioral …, 2019 - Elsevier
Uncertainty is often inevitable in everyday life and can be both stressful and exciting. Given
its relevance to psychopathology and wellbeing, recent research has begun to address the …

Task‐dependent uncertainty modulation of perceptual decisions in the human brain

S Li, F Yang - European Journal of Neuroscience, 2012 - Wiley Online Library
Perceptual judgments are frequently made during uncertain situations. Previous human
brain imaging studies have revealed multiple cortical and subcortical areas that are …

Decisions under uncertainty: probabilistic context influences activation of prefrontal and parietal cortices

SA Huettel, AW Song, G McCarthy - Journal of Neuroscience, 2005 - Soc Neuroscience
Many decisions are made under uncertainty; that is, with limited information about their
potential consequences. Previous neuroimaging studies of decision making have implicated …

The functional roles of the amygdala and prefrontal cortex in processing uncertainty

O FeldmanHall, P Glimcher, AL Baker… - Journal of Cognitive …, 2019 - direct.mit.edu
Decisions under uncertainty distinguish between those made under risk (known
probabilities) and those made under ambiguity (unknown probabilities). Despite widespread …

Neuroanatomical substrates for risk behavior

I Levy - The Neuroscientist, 2017 - journals.sagepub.com
Individuals vary substantially in their tendency to take risks. In the past two decades, a large
number of neuroimaging studies in humans have explored the neural mechanisms of …

Shifting uncertainty intolerance: methylphenidate and attention-deficit hyperactivity disorder

A Mandali, A Sethi, M Cercignani, NA Harrison… - Translational …, 2021 - nature.com
Risk evaluation is a critical component of decision making. Risk tolerance is relevant in both
daily decisions and pathological disorders such as attention-deficit hyperactivity disorder …