Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell-Derived Blood Cells—Ready for Take-Off

K Haake, M Ackermann… - Stem cells translational …, 2019 - academic.oup.com
Since their discovery in 2006, induced pluripotent stem cells (iPSCs) have opened up a
world of possibilities for regenerative medicine and novel cell-based therapeutics. Now, over …

Autologous blood cell therapies from pluripotent stem cells

C Lengerke, GQ Daley - Blood reviews, 2010 - Elsevier
The discovery of human embryonic stem cells (hESCs) raised promises for a universal
resource for cell based therapies in regenerative medicine. Recently, fast-paced progress …

[HTML][HTML] Efficient production of erythroid, megakaryocytic and myeloid cells, using single cell-derived iPSC colony differentiation

M Hansen, E Varga, C Aarts, T Wust, T Kuijpers… - Stem cell …, 2018 - Elsevier
Hematopoietic differentiation of human induced pluripotent stem cells (iPSCs) provide
opportunities not only for fundamental research and disease modelling/drug testing but also …

[HTML][HTML] Recent updates on induced pluripotent stem cells in hematological disorders

M Wattanapanitch - Stem cells international, 2019 - hindawi.com
Over the past decade, enormous progress has been made in the field of induced pluripotent
stem cells (iPSCs). Patients' somatic cells such as skin fibroblasts or blood cells can be used …

[HTML][HTML] Application of induced pluripotent stem cell technology to the study of hematological diseases

M Li, P Cascino, S Ummarino, A Di Ruscio - Cells, 2017 - mdpi.com
The burst of reprogramming technology in recent years has revolutionized the field of stem
cell biology, offering new opportunities for personalized, regenerative therapies. The direct …

Human‐induced pluripotent stem cell‐derived blood products: state of the art and future directions

M Hansen, M von Lindern, E van den Akker… - FEBS …, 2019 - Wiley Online Library
In vitro cultured blood cells for transfusion purposes provide a safe alternative to donor
blood, particularly for patients who require recurrent transfusions, and can be used as …

Induced pluripotent stem cell (iPSCs) and their application in immunotherapy

Z Jiang, Y Han, X Cao - Cellular & molecular immunology, 2014 - nature.com
The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …

Hematopoietic stem cells from pluripotent stem cells: Clinical potential, challenges, and future perspectives

S Demirci, A Leonard, JF Tisdale - Stem cells translational …, 2020 - academic.oup.com
The generation of hematopoietic stem cells (HSCs) from induced pluripotent stem cells
(iPSCs) is an active and promising area of research; however, generating engraftable HSCs …

[HTML][HTML] Induced pluripotent stem cells and personalized medicine: current progress and future perspectives

YS Chun, K Byun, B Lee - Anatomy & cell biology, 2011 - ncbi.nlm.nih.gov
Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of
regenerative medicine by providing researchers with a unique tool to derive disease-specific …

Human induced pluripotent stem cells: the past, present, and future

SMI Hussein, K Nagy, A Nagy - Clinical Pharmacology & …, 2011 - Wiley Online Library
A major breakthrough in the past 5 years is the development of the ability to reprogram
somatic cells to pluripotency. It has rejuvenated the field of stem cell research, providing …