We synthesised silica nanoparticles (SiNP) with covalently linked cationic surface
modifications and demonstrated their ability to electrostatically bind, condense and protect …

Diverse polycationic polymers have been used as nonviral transfection agents. Here we
report the ability of colloidal silica particles with covalently attached cationic surface …

In somatic gene therapy, new concepts for the transfer of DNA into specific cell nuclei are of
interest. Inorganic nanoparticles have an interesting potential as DNA carrier system due to …

The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

The transport of nucleic acid-based reagents is predicated upon developing structurally
stable delivery systems that can preferentially bind and protect DNA and RNA, and release …

This article reports a multidisciplinary approach to produce fluorescently labeled organically
modified silica nanoparticles as a nonviral vector for gene delivery and biophotonics …

Abstract Development of efficient molecular medicines, including gene therapeutics, RNA
therapeutics, and DNA vaccines, depends on efficient means of transfer of DNA or RNA into …

Silica nanoparticle supported cationic lipids can effectively bind plasmidDNAs and transfect
mammalian cells with an efficiency that depends on both the particle size and lipid …

Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …

Purpose To prepare mesoporous silica-based delivery systems capable of simultaneous
delivery of drugs and nucleic acids. Methods The surface of mesoporous silica nanoparticles …