Objective: To investigate whether polymorphisms in the interleukin (IL)-1 β and IL-1 receptor
antagonist (IL-1RA) genes are associated with both susceptibility to and clinical …

Article abstract The A1/A1 genotype of the anti-inflammatory cytokine interleukin 1 receptor
antagonist (IL-1Ra) polymorphism was more frequent in 339 Italian MS patients than in …

We studied the putative association of a C→ T polymorphism in exon-5 of IL-1β and an 85
bp tandem repeat in intron-4 of IL-1 receptor antagonist (IL-1ra) genes with susceptibility to …

Polymorphisms in the interleukin-1 genes, IL-1A and IL-1B, have been associated with AD,
but not in all studies. The authors genotyped the IL-1A (-889) and IL-1B (-511) …

Differential expression of interleukins may influence susceptibility to inflammatory diseases
such as MS. IL-1a production is increased in MS patients during acute relapse, IL-2 receptor …

In the present study, we have investigated the association of specific polymorphisms of the
interleukin (IL)-1β and IL-1 receptor antagonist (ra) gene with both the susceptibility to and …

Background: Multiple sclerosis (MS) is an autoimmune disorder, with a considerable genetic
influence on susceptibility and disease course. Cytokines play an important role in MS …

We studied the association between clinical outcome in MS and allelic variants single
nucleotide polymorphisms (SNPs) of interleukin-1α (IL-1α), IL-1β and a variable number …

In this explorative study, interleukin-1 (IL-1) receptor antagonist (IL-1RA; polymorphism of
variable number of tandem repeats: VNTR), IL-1α (− 889), IL-1β (− 511) and IL-1β (+ 3953) …

Materials and Methods: One hundred and twelve patients committed ischemic stroke were
compared with 95 demographically matched healthy volunteers. Results: The frequencies of …