Colistin against colistin-only-susceptible Acinetobacter baumannii-related infections: monotherapy or combination therapy?

F Şimşek, H Gedik, MT Yıldırmak, NE Iris… - Indian journal of medical …, 2012 - Elsevier
Purpose: To evaluate the outcomes of the patients who were infected with colistin-only-
susceptible (COS) Acinetobacter baumannii and treated with either colistin monotherapy or …

Colistin resistance in Acinetobacter baumannii isolated from critically ill patients: clinical characteristics, antimicrobial susceptibility and outcome

B Elham, A Fawzia - African health sciences, 2019 - ajol.info
Background: Acinetobacter baumannii (AB) is increasingly becoming a clinically relevant
organism due to the rising number of associated nosocomial infections. The therapeutic …

Synergistic activities of colistin combined with other antimicrobial agents against colistin-resistant Acinetobacter baumannii clinical isolates

MM Almutairi - PLoS One, 2022 - journals.plos.org
Emerging resistance to colistin in Acinetobacter baumannii clinical strains is concerning
because of the limited therapeutic choices for these important clinical pathogens. We …

Treatment Outcomes of Colistin- and Carbapenem-resistant Acinetobacter baumannii Infections: An Exploratory Subgroup Analysis of a Randomized Clinical Trial

Y Dickstein, J Lellouche… - Clinical Infectious …, 2019 - academic.oup.com
Background We evaluated the association between mortality and colistin resistance in
Acinetobacter baumannii infections and the interaction with antibiotic therapy. Methods This …

Colistin and rifampicin in the treatment of multidrug-resistant Acinetobacter baumannii infections

M Bassetti, E Repetto, E Righi, S Boni… - Journal of …, 2008 - academic.oup.com
Objectives The increased incidence of nosocomial infections by multidrug-resistant
organisms has motivated the re-introduction of colistin in combination with other …

Detection of colistin heteroresistance in Acinetobacter baumannii from blood and respiratory isolates

P Srinivas, LN Hunt, SM Pouch, K Thomas… - … and infectious disease, 2018 - Elsevier
Polymyxins are one of the last-line antibiotics for multidrug-resistant Acinetobacter
baumannii. Reports have demonstrated the emergence of colistin heteroresistance in A …

[HTML][HTML] Colistin monotherapy versus colistin/rifampicin combination therapy in pneumonia caused by colistin-resistant Acinetobacter baumannii: A randomised …

HJ Park, JH Cho, HJ Kim, SH Han, SH Jeong… - Journal of Global …, 2019 - Elsevier
Objectives The aim of this study was to confirm the synergistic effect of colistin/rifampicin
combination therapy compared with colistin monotherapy in pneumonia caused by colistin …

Meta-analysis of colistin for the treatment of Acinetobacter baumannii infection

Z Chen, Y Chen, Y Fang, X Wang, Y Chen, Q Qi… - Scientific reports, 2015 - nature.com
Multidrug resistant among Acinetobacter baumannii infection is associated with a high
mortality rate and limits the therapeutic options. The aim of this study was to assess the …

In vitro activity of colistin mono- and combination therapy against colistin-resistant Acinetobacter baumannii, mechanism of resistance, and clinical outcomes of patients infected …

Y Lertsrisatit, W Santimaleeworagun… - Infection and Drug …, 2017 - Taylor & Francis
Purpose Colistin is a drug of last resort for treating multidrug-resistant Acinetobacter
baumannii infections. Unfortunately, colistin-resistant A. baumannii (CoR-AB) has been …

In Vitro Synergistic Activity of Antimicrobial Agents in Combination against Clinical Isolates of Colistin-Resistant Acinetobacter baumannii

S Bae, MC Kim, SJ Park, HS Kim, H Sung… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Emerging resistance to colistin in clinical Acinetobacter baumannii isolates is of growing
concern. Since current treatment options for these strains are extremely limited, we …