CURCUMIN, THE ACTIVE PRINCIPLE OF TURMERIC (CURCUMA LONGA), AMELIORATES DIABETIC NEPHROPATHY IN RATS

S Sharma, SK Kulkarni, K Chopra - Clinical and experimental …, 2006 - Wiley Online Library
SUMMARY 1 Chronic hyperglycaemia in diabetes leads to the overproduction of free
radicals and evidence is increasing that these contribute to the development of diabetic …

Amelioration of renal lesions associated with diabetes by dietary curcumin in streptozotocin diabetic rats

PS Babu, K Srinivasan - Molecular and cellular biochemistry, 1998 - Springer
Curcumin, the coloring principle of the commonly used spice turmeric (Curcuma longa) was
fed at 0.5% in the diet to streptozotocin-induced diabetic Wistar rats for 8 weeks. Renal …

Amelioration of renal lesions associated with diabetes by dietary curcumin in streptozotocin diabetic rats.

K Srinivasan - Molecular and cellular biochemistry, 1998 - europepmc.org
Curcumin, the coloring principle of the commonly used spice turmeric (Curcuma longa) was
fed at 0.5% in the diet to streptozotocin-induced diabetic Wistar rats for 8 weeks. Renal …

Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats

P Murugan, L Pari - Basic & clinical pharmacology & toxicology, 2007 - Wiley Online Library
Curcumin is the most active component of turmeric. It is believed that curcumin is a potent
antioxidant and anti‐inflammatory agent. Tetrahydrocurcumin is one of the major …

[HTML][HTML] Renoprotective effect of the antioxidant curcumin: Recent findings

J Trujillo, YI Chirino, E Molina-Jijón… - Redox biology, 2013 - Elsevier
For years, there have been studies based on the use of natural compounds plant-derived as
potential therapeutic agents for various diseases in humans. Curcumin is a phenolic …

Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-κB

J Chiu, ZA Khan, H Farhangkhoee, S Chakrabarti - Nutrition, 2009 - Elsevier
OBJECTIVE: Diabetic nephropathy is a debilitating disease that leads to end-stage renal
failure in the Western world. Hyperglycemia is the initiating factor in several chronic diabetic …

Curcumin attenuates diabetic nephropathy by inhibiting PKC‐α and PKC‐β1 activity in streptozotocin‐induced type I diabetic rats

V Soetikno, K Watanabe, FR Sari… - Molecular nutrition & …, 2011 - Wiley Online Library
Scope: We hypothesized that curcumin, a potent anti‐oxidant, might be beneficial in
ameliorating the development of diabetic nephropathy through inhibition of PKC‐α and PKC …

Curcumin reverses glomerular hemodynamic alterations and oxidant stress in 5/6 nephrectomized rats

E Tapia, ZL Zatarain-Barrón, R Hernández-Pando… - Phytomedicine, 2013 - Elsevier
The administration of curcumin before and throughout the study attenuates oxidant stress
and glomerular hemodynamic alterations induced by 5/6 nephrectomy (5/6NX). The purpose …

[HTML][HTML] Protective effects of curcumin on renal oxidative stress and lipid metabolism in a rat model of type 2 diabetic nephropathy

BH Kim, ES Lee, R Choi, J Nawaboot… - Yonsei medical …, 2016 - ncbi.nlm.nih.gov
Purpose Diabetic nephropathy is a serious complication of type 2 diabetes mellitus, and
delaying the development of diabetic nephropathy in patients with diabetes mellitus is very …

Therapeutic potential of curcumin in diabetic complications

N Parsamanesh, M Moossavi, A Bahrami… - Pharmacological …, 2018 - Elsevier
Diabetes mellitus is an extremely prevalent endocrine disease and a major global public
health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and …