The effects of age, subcortical vascular disease, apolipoprotein E (APOE) ɛ4 allele and
hypertension on entorhinal cortex (ERC) and hippocampal atrophy rates were explored in a …

In the present study, as part of a more extensive longitudinal investigation of the in vivo
anatomical markers of early and incipient AD in our laboratory, three groups of elderly …

Objectives: To explore the atrophy rate of entorhinal cortex (ERC) in AD and normal aging
and assess the value of rate measurement of ERC atrophy for classifying subjects with AD …

Objectives: To determine if atrophy rates were higher for entorhinal cortex (ERC) than for
hippocampus in Alzheimer disease (AD), to determine the relationship between …

Using quantitative structural MRI protocols, we examined the effects of age on alterations in
entorhinal cortex (EC) volume. The left EC was found to be smaller than the right in both …

Objective: To test the hypothesis that entorhinal cortex (EC) volume decreases at a slower
rate than the hippocampal (HC) volume in healthy adults, and to examine whether the rate of …

Objectives: To determine the annual rates of volumetric change of the hippocampus and
temporal horn in cognitively normal elderly control subjects and individually matched …

Objective: To determine if baseline entorhinal and hippocampal volumes and their rate of
atrophy could predict the risk of incident Alzheimer disease (AD). Methods: The authors …

Objective: To evaluate the spatial pattern and regional rates of neocortical atrophy from
normal aging to early Alzheimer disease (AD). Methods: Longitudinal MRI data were …

Does accelerated cortical atrophy in aging, especially in areas vulnerable to early
Alzheimer's disease (AD), unequivocally signify neurodegenerative disease or can it be part …