Tumor necrosis factor: biology and therapeutic inhibitors
KA Papadakis, SR Targan - Gastroenterology, 2000 - Elsevier
Tumor necrosis factor (TNF) was originally described as a protein factor capable of killing
tumor cells in vitro and causing hemorrhagic necrosis of transplantable tumors in mice. 1, 2 …
tumor cells in vitro and causing hemorrhagic necrosis of transplantable tumors in mice. 1, 2 …
Tumour necrosis factor and Crohn's disease.
SJ Van Deventer - Gut, 1997 - ncbi.nlm.nih.gov
The production of several pro-inflammatory cytokines is increased in inflammatory bowel
diseases (IBD). Experimental models of IBD have further defined the importance of specific …
diseases (IBD). Experimental models of IBD have further defined the importance of specific …
Transmembrane TNF-α, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn's disease
SJH Van Deventer - Gastroenterology, 2001 - Elsevier
Tumor necrosis factor (TNF)-α is a potent proinflam-matory cytokine that orchestrates
inflammatory responses by activating a wide range of cells. These effects are mediated by …
inflammatory responses by activating a wide range of cells. These effects are mediated by …
[HTML][HTML] Study of tumor necrosis factor receptor in the inflammatory bowel disease
RF Souza, MAF Caetano, HIR Magalhães… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) and Crohn's disease (CD) are part of Inflammatory Bowel Diseases
(IBD) and have pathophysiological processes such as bowel necrosis and enteric neurons …
(IBD) and have pathophysiological processes such as bowel necrosis and enteric neurons …
[HTML][HTML] Molecular mechanism of action of anti-tumor necrosis factor antibodies in inflammatory bowel diseases
U Billmeier, W Dieterich, MF Neurath… - World journal of …, 2016 - ncbi.nlm.nih.gov
Anti-tumor necrosis factor (TNF) antibodies are successfully used in the therapy of
inflammatory bowel diseases (IBD). However, the molecular mechanism of action of these …
inflammatory bowel diseases (IBD). However, the molecular mechanism of action of these …
Integrating anti–tumor necrosis factor therapy in inflammatory bowel disease: current and future perspectives
ME Blam, RB Stein, GR Lichtenstein - Official journal of the …, 2001 - journals.lww.com
Crohn's disease and ulcerative colitis are two idiopathic inflammatory disorders of the GI
tract. Manifestations of disease can be severe and lead to long term therapy with a variety of …
tract. Manifestations of disease can be severe and lead to long term therapy with a variety of …
Tumor necrosis factor inhibitors for inflammatory bowel disease
OH Nielsen, MA Ainsworth - New England Journal of Medicine, 2013 - Mass Medical Soc
Tumor Necrosis Factor Inhibitors for Inflammatory Bowel Disease | NEJM Skip to main content
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NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …
[HTML][HTML] Tumor necrosis factor inhibitors
V Gerriets, A Goyal, K Khaddour - 2018 - europepmc.org
Tumor Necrosis Factor Inhibitors - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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Tumor necrosis factor: function, release and clearance
MHA Bemelmans, LJH Van Tits… - Critical Reviews™ in …, 1996 - dl.begellhouse.com
ABSTRACT Tumor Necrosis Factor (TNF) is a multifunctional cytokine. It plays an important
role in the pathophysiology of several diseases. Recently, it has been discovered that TNF is …
role in the pathophysiology of several diseases. Recently, it has been discovered that TNF is …
Mechanisms behind efficacy of tumor necrosis factor inhibitors in inflammatory bowel diseases
CM Olesen, M Coskun, L Peyrin-Biroulet… - Pharmacology & …, 2016 - Elsevier
Biological treatment with tumor necrosis factor (TNF) inhibitors is successful in the
management of inflammatory bowel disease (IBD). All TNF inhibitors antagonize the pro …
management of inflammatory bowel disease (IBD). All TNF inhibitors antagonize the pro …