Filling the gap: Evidence for a spatial differentiation in trace eyeblink conditioning

MF Larra, A Behrje, JB Finke, TD Blumenthal… - Neuroscience …, 2017 - Elsevier
Trace eyeblink conditioning is used as a translational model of declarative memory but
restricted to the temporal domain. Potential spatial aspects have never been experimentally …

Awareness is necessary for differential trace and delay eyeblink conditioning in humans

PF Lovibond, JCJ Liu, G Weidemann, CJ Mitchell - Biological Psychology, 2011 - Elsevier
Squire et al. have proposed that trace and delay eyeblink conditioning procedures engage
separate learning systems: a declarative hippocampal/cortical system associated with …

Human eyeblink classical conditioning: Effects of manipulating awareness of the stimulus contingencies

RE Clark, LR Squire - Psychological science, 1999 - journals.sagepub.com
In four groups, we either promoted or prevented awareness of the stimulus contingencies
during trace or delay differential eyeblink classical conditioning. To reduce awareness of the …

Parallel acquisition of awareness and trace eyeblink classical conditioning

JR Manns, RE Clark, LR Squire - Learning & Memory, 2000 - learnmem.cshlp.org
Trace eyeblink conditioning (with a trace interval≥ 500 msec) depends on the integrity of
the hippocampus and requires that participants develop awareness of the stimulus …

Awareness predicts the magnitude of single‐cue trace eyeblink conditioning

JR Manns, RE Clark, LR Squire - Hippocampus, 2000 - Wiley Online Library
Studies of differential eyeblink conditioning (CS+ and CS‐) have demonstrated that
successful conditioning requires awareness of the stimulus contingencies and that delay …

Trace and delay eyeblink conditioning: Contrasting phenomena of declarative and nondeclarative memory

RE Clark, JR Manns, LR Squire - Psychological science, 2001 - journals.sagepub.com
We tested the proposal that trace and delay eyeblink conditioning are fundamentally
different kinds of learning. Strings of one, two, three, or four trials with the conditioned …

Cellular alterations in hippocampus during acquisition and consolidation of hippocampus-dependent trace eyeblink conditioning

JF Disterhoft, MD McEchron - Eyeblink Classical Conditioning: Volume 2 …, 2002 - Springer
The hippocampus has been of particular interest for studies of memory since Scoville and
Milner (1957) reported the profound amnesia of patient HM following bilateral resection of …

Awareness and the conditioned eyeblink response

RE Clark, LR Squire - … Classical Conditioning: Volume I: Applications in …, 2000 - Springer
Conclusion Classical conditioning of the eyeblink response in both humans and
experimental animals has provided an enormous amount of information about basic …

Neural substrates underlying human delay and trace eyeblink conditioning

DT Cheng, JF Disterhoft, JM Power… - Proceedings of the …, 2008 - National Acad Sciences
Classical conditioning paradigms, such as trace conditioning, in which a silent period
elapses between the offset of the conditioned stimulus (CS) and the delivery of the …

Trace eyeblink conditioning in mice is dependent upon the dorsal medial prefrontal cortex, cerebellum, and amygdala: behavioral characterization and functional …

JJ Siegel, W Taylor, R Gray, B Kalmbach… - ENeuro, 2015 - eneuro.org
Trace eyeblink conditioning is useful for studying the interaction of multiple brain areas in
learning and memory. The goal of the current work was to determine whether trace eyeblink …