Mutation of the DNA-binding region of the FOXP2 protein causes an inherited language
disorder. A recent study provides the first data on mice with this mutation, which exhibit …

Disruption of FOXP2, a gene encoding a forkhead‐domain transcription factor, causes a
severe developmental disorder of verbal communication, involving profound articulation …

Disruptions of the human FOXP2 gene cause problems with articulation of complex speech
sounds, accompanied by impairment in many aspects of language ability. The FOXP2/Foxp2 …

Highlights•Mutations of the FOXP2 gene cause a severe speech and language
disorder.•Mice with Foxp2 disruptions have provided valuable insights into its …

FOXP2, the first gene to have been implicated in a developmental communication disorder,
offers a unique entry point into neuromolecular mechanisms influencing human speech and …

Mutations in the FOXP2 gene cause a severe communication disorder involving speech
deficits (developmental verbal dyspraxia), accompanied by wide-ranging impairments in …

The rise of genomic technologies has yielded exciting new routes for studying the biological
foundations of language. Researchers have begun to identify genes implicated in …

Foxp subfamily genes were recently recognized to be members of the Fox gene family. Foxp
subfamily members contain a zinc finger domain and a leucine zipper motif in addition to a …

The most well-described example of an inherited speech and language disorder is that
observed in the multigenerational KE family, caused by a heterozygous missense mutation …

Intact function of the Forkhead Box P2 (FOXP2) gene is necessary for normal development
of speech and language. This important role has recently been extended, first to other forms …