The role of neuronal nitric oxide synthase on hypobaric hypoxiainduced antinociception in writhing test

SM Choi, SY Chung, CA Seol, JG Sul… - Archives of pharmacal …, 2010 - Springer
It has been reported that hypobaric hypoxia exposure by high altitude is responsible for
neuropsychological impairment. In the present study, we examined an effect of hypobaric …

The acute antinociceptive effect of HBO2 is mediated by a NO–cyclic GMP–PKG–KATP channel pathway in mice

LP Quock, Y Zhang, E Chung, Y Ohgami, DY Shirachi… - Brain research, 2011 - Elsevier
Previous research has found that hyperbaric oxygen (HBO2) produces an acute
antinociceptive effect that is dependent on nitric oxide (NO). The present study was …

Nitric oxide in hyperbaric oxygen-induced acute antinociception in mice

Y Ohgami, CC Zylstra, LP Quock, E Chung… - …, 2009 - journals.lww.com
Abstract Hyperbaric oxygen (HBO 2) therapy induces analgesia in various conditions of pain
in humans. In mice, HBO 2 treatment evokes an acute antinociceptive response in the …

Effects of acute hypobaric hypoxia on the nitric oxide system of the rat cerebral cortex: Protective role of nitric oxide inhibitors

J Serrano, JM Encinas, AP Fernandez, J Rodrigo… - Neuroscience, 2006 - Elsevier
Exposure to hypobaric hypoxia produces neuropsychological disorders. The brain nitrergic
system was investigated following hypobaric hypoxia in the presence or absence of nitric …

Involvement of spinal cord opioid mechanisms in the acute antinociceptive effect of hyperbaric oxygen in mice

JH Heeman, Y Zhang, DY Shirachi, RM Quock - Brain research, 2013 - Elsevier
Earlier research has demonstrated that treatment with hyperbaric oxygen (HBO 2) can elicit
an antinociceptive response in models of acute pain. We have demonstrated that this …

The acute antinociceptive effect of hyperbaric oxygen is not accompanied by an increase in markers of oxidative stress

S Liu, DY Shirachi, RM Quock - Life sciences, 2014 - Elsevier
Aims Exposure to hyperbaric oxygen (HBO 2) causes an antinociceptive response in mice.
However, breathing oxygen (O 2) at an elevated pressure can potentially cause oxygen …

Hyperbaric oxygen produces a nitric oxide synthase-regulated anti-allodynic effect in rats with paclitaxel-induced neuropathic pain

Y Zhang, AL Brewer, JT Nelson, PT Smith, DY Shirachi… - Brain research, 2019 - Elsevier
Research has demonstrated that hyperbaric oxygen (HBO 2) treatment produced relief of
both acute and chronic pain in patients and animal models. However, the mechanism of …

An anxiolytic-like effect of hyperbaric oxygen in the mouse light/dark exploration test

EL Carlile, DY Shirachi, RM Quock - Life sciences, 2012 - Elsevier
AIMS: We studied whether hyperbaric oxygen (HBO2) treatment, which is known to increase
production of nitric oxide (NO) in the brain, might also produce an NO-dependent anxiolytic …

The Nitric oxide/CGMP/KATP pathway mediates systemic and central antinociception induced by resistance exercise in rats

GS Galdino, CH Xavier, R Almeida, G Silva… - International Journal …, 2015 - Taylor & Francis
Resistance exercise (RE) is characterized to increase strength, tone, mass, and/or muscular
endurance and also for produces many beneficial effects, such as blood pressure and …

The Acute Antinociceptive Effect of Hyperbaric Oxygen (HBO2) Is Not Accompanied by an Increase in Markers of Oxidative Stress

S Liu, CC Zylstra, DY Shirachi, RM Quock - 2013 - Wiley Online Library
Exposure to 3.5 ATA HBO2 causes antinociception in mice (Ohgami et al., NeuroReport 20:
1325, 2010). However, breathing O2 at an elevated pressure can potentially cause oxygen …