Glutamate and dopamine receptors contribute to the lateral spread of epileptiform discharges in rat neocortical slices

M Goda, S Kovac, EJ Speckmann, A Gorji - Epilepsia, 2008 - Wiley Online Library
Purpose: The effects of AMPA‐type glutamate receptor as well as dopamine D1 and D2
receptors on the lateral propagation of epileptiform field potentials (EFP) were studied …

Pattern and pharmacology of propagating epileptiform activity in mouse cerebral cortex

M Alefeld, B Sutor, HJ Luhmann - Experimental neurology, 1998 - Elsevier
Multiple extracellular recording electrodes were used to study the intra-and interhemispheric
spread of stimulus-evoked epileptiform responses in adult mouse neocortical slices. Bath …

Epileptiform propagation patterns mediated by NMDA and non‐NMDA receptors in rat neocortex

AE Telfeian, BW Connors - Epilepsia, 1999 - Wiley Online Library
Purpose: The neocortex can generate various forms of epileptiform activity, including one
that depends on N‐methyl‐D‐aspartate (NMDA)‐type glutamate receptors (NMDARs), and …

The lateral spread of ictal discharges in neocortical brain slices

BY Wong, DA Prince - Epilepsy research, 1990 - Elsevier
The in vitro brain slice technique was used to examine the lateral propagation of
spontaneous electrographic ictal episodes across adjacent areas of guinea pig neocortex …

Layer‐specific pathways for the horizontal propagation of epileptiform discharges in neocortex

AE Telfeian, BW Connors - Epilepsia, 1998 - Wiley Online Library
Purpose: Epileptiform discharges that resemble interictal spikes can be generated by slices
of neocortex treated with antagonists of γ‐aminobutyric acid A (GABAA) receptors. These …

Changes in excitatory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy

EW Lothman, DA Rempe… - Journal of …, 1995 - journals.physiology.org
1. In this report we compare changes of excitatory neurotransmission within the CA1 region
and the dentate gyrus (DG) in a model of chronic temporal lobe epilepsy (TLE). Extracellular …

Neocortical slices from adult chronic epileptic rats exhibit discharges of higher voltages and broader spread

R Serafini, S Dettloff, JA Loeb - Neuroscience, 2016 - Elsevier
Much of the current understanding of epilepsy mechanisms has been built on data recorded
with one or a few electrodes from temporal lobe slices of normal young animals stimulated …

Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy

PS Mangan, DA Rempe… - Journal of …, 1995 - journals.physiology.org
1. In this report we compare changes in inhibitory neurotransmission within the CA1 region
and the dentate gyrus (DG) in a model of chronic temporal lobe epilepsy (TLE). Extracellular …

The influence of dopamine of epileptiform burst activity in hippocampal pyramidal neurons

T Suppes, AR Kriegstein, DA Prince - Brain research, 1985 - Elsevier
Dopamine (DA) application to guinea pig hippocampal CA1 neurons in vitro causes
hyperpolarization of the resting potential, increase in conductance, and increase in …

Enhanced propagation of epileptiform activity through the kindled dentate gyrus

J Behr, KJ Lyson, I Mody - Journal of neurophysiology, 1998 - journals.physiology.org
Behr, J., KJ Lyson, and I. Mody. Enhanced propagation of epileptiform activity through the
kindled dentate gyrus. J. Neurophysiol. 79: 1726–1732, 1998. Extracellular recordings were …