Abstract Objectives The 29-item Multiple Sclerosis Impact Scale (MSIS-29) is a
psychometrically validated patient-reported outcome measure increasingly used in trials of …

Purpose The three most widely used utility measures are the Health Utilities Index Mark 2
and 3 (HUI2 and HUI3), the EuroQol-5D (EQ-5D) and the Short-Form-6D (SF-6D). In line …

Objectives This study responds to a request in the National Institute for Health and Care
Excellence (NICE) guidance to assess the impact of using alternative sources of utility …

Background Condition-specific measures are frequently used to assess the health-related
quality of life of people with multiple sclerosis (MS). Such measures are unsuitable for use in …

abstract Objectives To estimate health state utility values (HSUVs) for multiple sclerosis (MS)
by key demographic and clinical characteristics. Methods Data from a UK prospective …

Background Increasingly, generic preference-based measures of health-related quality of
life (HRQOL) are used to estimate quality-adjusted life-years to inform resource allocation …

Objective In economic evaluation, health outcomes are commonly quantified using quality-
adjusted life-years (QALYs) derived from the preferences of a sample of the general …

Background: Increasing use of the Quality-Adjusted Life-Year to inform resource allocation
decision-making has highlighted the importance of relating clinical and health-related …

Background: The measurement of health state utility values (HSUVs) for a representative
sample of Australian people with multiple sclerosis (MS) has not previously been performed …

Background Health state utilities (HSU) are a health-related quality-of-life (HRQoL) input for
cost-utility analyses used for resource allocation decisions, including medication …