Dihydroxyvitamin D3 (1, 25 (OH) 2D3)-mediated intestinal calcium (Ca) absorption supplies
Ca for proper bone mineralization during growth. We tested whether vitamin D receptor …

BACKGROUND & AIMS: Vitamin D receptor (VDR)-knockout mice develop severe
hypocalcemia and rickets, accompanied by disruption of active intestinal calcium absorption …

ABSTRACT 1, 25 Dihydroxyvitamin D3 (1, 25 (OH) 2D) increases intestinal Ca absorption
when dietary Ca intake is low by inducing gene expression through the vitamin D receptor …

Although the intestine plays the major role in 1, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3]
action on calcium homeostasis, the mechanisms involved remain incompletely understood …

To study the role of calbindin D 9k (CaBP) and epithelial calcium channel ECaC2 in
intestinal calcium (Ca) absorption, vitamin D receptor knockout (KO) and wild-type (WT) …

The active form of vitamin D, 1, 25 (OH) 2 D, is a crucial regulator of calcium homeostasis,
especially through stimulation of intestinal calcium transport. Lack of intestinal vitamin D …

The serum calcium levels and the calcium content of the skeleton are highly interdependent.
Indeed, bone requires calcium to preserve its strength, but it is at the same time also the …

Serum calcium levels are tightly controlled by an integrated hormone-controlled system that
involves active vitamin D [1, 25 (OH) 2D], which can elicit calcium mobilization from bone …

1, 25 (OH) 2D3 regulates calcium homeostasis through its actions in the intestine, bone, and
kidney. These actions are mediated through the VDR. To determine if VDR's actions in the …

The effects of the dietary Ca and P ratio, independent of any vitamin D effects, on bone
mineralization and turnover was examined in 60 VDRKO mice fed different Ca/P ratio diets …