Biosynthesis investigations of terpenoid, alkaloid, and flavonoid antimicrobial agents derived from medicinal plants

W Huang, Y Wang, W Tian, X Cui, P Tu, J Li, S Shi… - Antibiotics, 2022 - mdpi.com
The overuse of antibiotics in the past decades has led to the emergence of a large number
of drug-resistant microorganisms. In recent years, the infection rate caused by multidrug …

Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?

CL Gorlenko, HY Kiselev, EV Budanova… - Antibiotics, 2020 - mdpi.com
Infectious diseases that are caused by bacteria are an important cause of mortality and
morbidity in all regions of the world. Bacterial drug resistance has grown in the last decades …

Secondary plant metabolites as potent drug candidates against antimicrobial-resistant pathogens

K Keita, C Darkoh, F Okafor - SN Applied Sciences, 2022 - Springer
Antibiotic resistance is a major public health threat of the twenty-first century and represents
an important risk to the global economy. Healthcare-associated infections mainly caused by …

Plant-derived antimicrobial compounds: alternatives to antibiotics

D Savoia - Future microbiology, 2012 - Future Medicine
The increasing incidence of drug-resistant pathogens has drawn the attention of the
pharmaceutical and scientific communities towards studies on the potential antimicrobial …

Antimicrobial diterpenes: Recent development from natural sources

P Saha, FI Rahman, F Hussain… - Frontiers in …, 2022 - frontiersin.org
Antimicrobial resistance has been posing an alarming threat to the treatment of infectious
diseases over the years. Ineffectiveness of the currently available synthetic and …

Plant natural products as a potential source for antibacterial agents: recent trends

M Shahid, A Shahzad, F Sobia, A Sahai… - Anti-Infective Agents …, 2009 - ingentaconnect.com
Pasteur and Joubert, in 1877, were among the first to recognize the potential of microbial
products as therapeutic agents and demonstrated that common microorganisms could …

Ethnobotany and the role of plant natural products in antibiotic drug discovery

G Porras, F Chassagne, JT Lyles, L Marquez… - Chemical …, 2020 - ACS Publications
The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

Antimicrobial plant metabolites: structural diversity and mechanism of action

NS Radulovic, PD Blagojevic… - Current medicinal …, 2013 - ingentaconnect.com
Microbial infectious diseases continue to be one of the leading causes of morbidity and
mortality. It has been estimated that microbial species comprise about 60% of the Earth's …

Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives

N Vaou, E Stavropoulou, C Voidarou, C Tsigalou… - Microorganisms, 2021 - mdpi.com
The increasing incidence of drug-resistant pathogens raises an urgent need to identify and
isolate new bioactive compounds from medicinal plants using standardized modern …

The revaluation of plant-derived terpenes to fight antibiotic-resistant infections

F Cappiello, MR Loffredo, C Del Plato, S Cammarone… - Antibiotics, 2020 - mdpi.com
The discovery of antibiotics has revolutionized the medicine and treatment of microbial
infections. However, the current scenario has highlighted the difficulties in marketing new …