The hypothesis that only melanosomal catecholic amino acids contribute to melanin
formation was tested by studying adult bovine eyes in which pigment synthesis is …

The concentration of dopa, dopamine and cysteinyldopa were measured in various parts of
the mature bovine eye, using a fluorescent assay. Special attention was paid to …

To explore the possibility that dopa and 5-S-cysteinyldopa, precursors of melanin, can be
produced in non-melanogenic tissues, this study examined the contents of the free and …

Dopa and 5-S-cysteinyldopa levels in serum of albino, red, and black guinea-pigs were
quantified. The levels of both amino acids were lower in the albino than in the pigmented …

Norepinephrine and dopamine content of various tissues from albine and nonalbino (black
fur) rabbits were chemically determined. Although norepinephrine content of the …

The tyrosinase activity in melanin‐forming tissues was investigated in a series of rats (6 days
to 1 year old), one cat 30 days old, and one 4 month old human fetus. The technique used …

Cultured melanoma cells have been of great value in the study of pigment metabolism. IGR
1 human melanoma cells, established by Dr Christian Aubert, produce melanin in large …

Modern techniques offer an opportunity for a more complete evaluation of melanin
production in the uvea and retinal pigment epithelium (RPE). By measuring the release of …

Electron microscopic autoradiography was used to investigate the relationship between
melanin formation and thiol incorporation in premelanosomes of genetically defined chick …

Melanocytes contain several substances formed by the nucleophilic addition of cysteine to
dopaquinone. 5‐S‐Cysteinyldopa is the quantitatively dominant catecholic amino acid …