Effect of Gefitinib on Brain Metastases From Non-Small Cell Lung Cancer-Two Case Reports

N Noriyuki, K Shozo, Y Taiji, F Kenta… - Neurologia medico …, 2006 - cir.nii.ac.jp
抄録 Two patients with non-small cell lung cancer presented with multiple brain metastases.
They received gefitinib orally for the treatment of the primary lung lesions. About one month …

Effect of Gefitinib on Brain Metastases From Non-Small Cell Lung Cancer—Two Case Reports—

N Nishi, S Kawai, T Yonezawa, K Fujimoto… - Neurologia medico …, 2006 - jstage.jst.go.jp
Two patients with non-small cell lung cancer presented with multiple brain metastases. They
received gefitinib orally for the treatment of the primary lung lesions. About one month later …

Brain metastasis responding to gefitinib alone

ANY Poon, SSM Ho, W Yeo, TSK Mok - Oncology, 2004 - karger.com
A woman with stage IIIb non-small cell lung cancer (NSCLC) developed disease
progression with brain metastases during chemotherapy. Due to unusual circumstances, the …

Gefitinib in patients with brain metastases from non–small-cell lung cancer: review of 15 clinical cases

Y Namba, T Kijima, S Yokota, M Niinaka… - Clinical lung cancer, 2004 - Elsevier
The clinical efficacy of gefitinib, a tyrosine kinase inhibitor of epidermal growth factor
receptor (EGFR), on brain metastases (BMs) from non–small-cell lung cancer (NSCLC) was …

Gefitinib as a first line of therapy in non-small cell lung cancer with brain metastases

A Ishida, K Kanoh, T Nishisaka, Y Miyazu… - Internal …, 2004 - jstage.jst.go.jp
Two Japanese women were diagnosed as having welldifferentiated adenocarcinoma of the
lung with brain metastases. Since it was considered they could not tolerate conventional …

Two cases of non-small cell lung cancer which developed central nervous system metastases during gefitinib treatment, improving after changing to erlotinib treatment

K Kunimasa, H Yoshioka, M Iwasaku… - Nihon Kokyuki Gakkai …, 2010 - europepmc.org
We report two cases of central nervous system metastases from non-small cell lung cancer
in patients being administered gefitinib, which improved after changing treatment to erlotinib …

Two lung adenocarcinoma patients with multiple brain metastasis treated with gefitinib and surviving more than 2 years

W Matsuyama, M Yamamoto, K Machida… - Nihon Kokyuki Gakkai …, 2006 - europepmc.org
Case 1 is a 78-year-old woman in whom lung adenocarcinoma with multiple brain
metastasis (cT2N3M1, stage IV) was diagnosed. She was treated with Gefitinib alone. Her …

Brain metastases in metastatic non-small cell lung cancer responding to single-agent gefitinib: a case report

HJ Stemmler, O Weigert, M Krych… - Anti-cancer …, 2005 - journals.lww.com
Brain metastases are a frequent finding in patients with non-small cell lung cancer (NSCLC).
The present case reports the clinical course of a patient who was treated with gefitinib alone …

A case of leptomeningeal metastasis from adenocarcinoma of the lung improved by treatment with Gefitinib

SK Yu, WJ Park, CS Park, HJ Chin, KC Shin… - The Korean Journal of …, 2008 - ekjm.org
Leptomeningeal metastasis occurs in approximately 1% of patients with non-small cell lung
cancer and this is an extremely serious complication. Without treatment, the median survival …

Activity of Gefitinib in Central Nervous System Metastases in Patients with Non–Small-Cell Lung Cancer: Two Case Reports and a Review of the Literature

A Gurpide, JL Perez-Gracia, JM Lopez-Picazo… - Clinical lung cancer, 2005 - Elsevier
Gefitinib is the first inhibitor of the epidermal growth factor receptor that has shown activity in
non–small-cell lung cancer (NSCLC), but its potential value in the treatment of central …