Congenital neutropenia (CN) is a genetic disorder characterized by persistent or intermittent
low peripheral neutrophil counts, thus increasing susceptibility to bacterial and fungal …

Background: Congenital neutropenia (CN) is a group of rare inborn genetic disorders of
hematopoiesis including a variety of different gene mutations and different patterns of …

Severe congenital neutropenia (CN) includes a variety of hematologic disorders
characterized by severe neutropenia, with absolute neutrophil counts (ANC) below 0.5× …

OBJECTIVE: More than 90% of patients with severe congenital neutropenia (SCN) respond
to granulocyte colony-stimulating factor (G-CSF) therapy. The basis for the refractory state in …

Severe congenital neutropenia (SCN) is a genetically heterogeneous condition of bone
marrow failure usually diagnosed in early childhood and characterized by a chronic and …

Severe congenital neutropenia (SCN) comprises a heterogenous group of primary
immunodeficiency disorders collectively characterized by paucity of mature neutrophils. In …

Severe congenital neutropenia (SCN) is a rare disease diagnosed at or soon after birth,
characterized by a myeloid maturation arrest in the bone marrow, ineffective neutrophil …

Neutropenia is a hematological condition characterized by a decrease in absolute
neutrophil count (ANC) in peripheral blood, typically classified in adults as mild (1-1.5× 10 …

Severe congenital neutropenia (SCN) is a heterogeneous disease condition with a variable
family history and a propensity to progress towards myelodysplastic syndrome (MDS) and …

Over the last 25 years, with the clinical approval of recombinant human granulocyte colony-
stimulating factor (rhG-CSF) remarkable progress has been achieved in the therapy of …