The tachykinin family of vasoactive peptides comprises the neuropeptides substance P,
neurokinin A and neurokinin B, and the newly discovered endokinins and hemokinins. Their …

抄録 Substance P and neurokinin A are tachykinins that are co-localized with calcitonin
gene-related peptide (CGRP) in a unique subpopulation of cardiac afferent nerve fibers …

Kinins are synthesized from their precursors by different enzymes and participate in the
regulation of cardiovascular function through bradykinin (BK) B1 and B2 receptors. They …

Endogenous kinins are important vasoactive peptides whose effects are mediated by two G-
Protein-coupled receptors (R), named B2R (constitutive) and B1R (inducible). They are …

Angiotensins and kinins are endogenous peptides with diverse biological actions; as such,
they represent current and future targets of therapeutic intervention. The field of angiotensin …

Tachykinins constitute a family of neuropeptides which share the common C-terminal
sequence Phe-Xaa-Gly-Leu-Met-NH2. This sequence is critical for their interaction with …

We report four human tachykinins, endokinins A, B, C, and D (EKA–D), encoded from a
single tachykinin precursor 4 gene that generates four mRNAs (α, β, γ, and δ). Tachykinin 4 …

Autocrine, paracrine, endocrine, and neuroendocrine hormonal systems help regulate
cardio‐vascular and renal function. Any change in the balance among these systems may …

The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

Human hemokinin-1 and its carboxy-terminal fragment human hemokinin-1 (4-11) have
been recently identified as the members of the tachykinin family. The peripheral …