METHODS Animals and study protocol. Male C57BL/6J mice were obtained from Charles
River (Maastricht, The Netherlands) at 7 wk of age. The mice were fed a standard growth …

The aim of this study was to characterize the responses of individual tissues to high fat 23
feeding as a function of mass, fat composition and transcript abundance. We examined a 24 …

Using standardized, semipurified diets is a crucial factor for reproducibility of experimental
nutritional studies. For the purpose of comparability and integration of research, two …

After three decades of physiological research, the precise nature of the genetic lesion in
Zucker fatty (fa/fa) rats remains unknown. Several methods have been used to identify …

In order to characterize mechanisms responsible for fat accumulation we used a 50
selectively bred obesity-prone (OP) and obesity-resistant (OR) rat model, where 51 the rats …

Obesity is the most common nutritional disorder and is associated with a cluster of chronic
metabolic disorders such as dyslipidemia, atherosclerosis, and type 2 diabetes. As a part of …

Background Exercise has been shown in pre‐clinical models to attenuate weight regain by
reducing food intake and increasing energy expenditure beyond the cost of the exercise …

Obesity has become a major health risk factor worldwide. The tendency of gaining weight is
influenced by the genetic predisposition and the environment. We used the high body …

Obesity and its associated low grade inflammation is a major risk factor for the development
of many diseases including type 2 diabetes, nonalcoholic fatty liver disease, and …

Obesity is a potential risk factor for a various disease such as cardiovascular disease,
diabetes, renal disease, hypertension, cancer, and neural disease. Animals on the adipose …