Non-vitamin K antagonist oral anticoagulants (NOACs) versus warfarin in patients with atrial fibrillation and (morbid) obesity or low body weight: a systematic review …

M Grymonprez, TL De Backer, S Steurbaut… - … Drugs and Therapy, 2021 - Springer
Purpose Oral anticoagulants are crucial for preventing systemic thromboembolism in atrial
fibrillation (AF), with guidelines preferring non-vitamin K antagonist oral anticoagulants …

Clinical performance of nonvitamin K antagonist oral anticoagulants in real-world obese patients with atrial fibrillation

V Russo, R Bottino, A Rago, AA Papa… - … in Thrombosis and …, 2020 - thieme-connect.com
The prevalence of both atrial fibrillation (AF) and obesity has steadily increased. Nonvitamin
K antagonist oral anticoagulants (NOACs) have been shown to be more effective and safer …

The safety and efficacy of nonvitamin K antagonist oral anticoagulants in morbidly obese patients with atrial fibrillation: a meta-analysis

S Elfar, SA Mahmoud, S Hamdi, AA Emad… - BMC Cardiovascular …, 2024 - Springer
Background and aim Atrial fibrillation (AF) is the most frequently observed cardiac
arrhythmia in clinical settings. Obesity can influence the efficacy of the treatment …

Increased risk of major bleeding in underweight patients with atrial fibrillation who were prescribed non-vitamin K antagonist oral anticoagulants

CS Park, EK Choi, HM Kim, SR Lee, MJ Cha, S Oh - Heart Rhythm, 2017 - Elsevier
Background There is a paucity of evidence regarding the effects of non-vitamin K antagonist
oral anticoagulants (NOACs) in underweight patients with atrial fibrillation (AF). Objective …

Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual …

SM Patel, E Braunwald, J Steffel, G Boriani… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The efficacy and safety of non–vitamin-K antagonist oral anticoagulants
(NOACs) across the spectrum of body mass index (BMI) and body weight (BW) remain …

Efficacy and safety of direct oral anticoagulant in morbidly obese patients with atrial fibrillation: systematic review and meta-analysis

S Thangjui, J Kewcharoen, R Yodsuwan… - European Heart …, 2022 - academic.oup.com
Aims We conducted a systematic review and meta-analysis on three outcomes. We
assessed the efficacy and safety of direct oral anticoagulants (DOAC) compared to vitamin K …

Non-vitamin K antagonist oral anticoagulant for atrial fibrillation in obese patients

SY Wang, RP Giugliano - The American Journal of Cardiology, 2020 - Elsevier
Highlights•Obesity is an important risk factor for atrial fibrillation.•Despite “obesity paradox”
in atrial fibrillation, patient weight loss preferred.•Oral anticoagulants may be more …

Impact of weight on the efficacy and safety of direct-acting oral anticoagulants in patients with non-valvular atrial fibrillation: a meta-analysis

AH Malik, S Yandrapalli, S Shetty, WS Aronow… - EP …, 2020 - academic.oup.com
Aims This study sought to determine the impact of weight and body mass index (BMI) on the
safety and efficacy of direct-acting oral anticoagulants (DOACs) compared with warfarin in …

Is There an Obesity Paradox for Outcomes in Atrial Fibrillation? A Systematic Review and Meta-Analysis of Non–Vitamin K Antagonist Oral Anticoagulant Trials

M Proietti, E Guiducci, P Cheli, GYH Lip - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Obesity is a risk factor for all-cause and cardiovascular death
but, despite this, an inverse relationship between overweight or obesity and a better …

Efficacy and safety of direct oral anticoagulants versus warfarin in patients with atrial fibrillation across BMI categories: a systematic review and meta-analysis

Y Zhou, J Ma, W Zhu - American Journal of Cardiovascular Drugs, 2020 - Springer
Objectives Concerns have arisen recently over the relationship between body mass index
(BMI) and outcomes in atrial fibrillation (AF) patients with direct oral anticoagulants (DOACs) …