We reported previously that onset of oligodendrocyte precursor cell (OPC) differentiation is
accompanied by an increase in intracellular pH (pHi). We show that OPC differentiation is …

Oligodendrocytes differentiate on a specific schedule in vivo in order to myelinate axons at
the precise time and at the appropriate position. The current study was undertaken to obtain …

Oligodendrocytes generate and maintain myelin, which is essential for axonal function and
protection of the mammalian central nervous system. To advance our molecular …

We have studied the characteristics of pHi regulation at different stages of rat
oligodendrocyte differentiation in primary culture. pHi was measured at 37° C using the pH …

The successive stages of development from oligodendrocyte progenitor to mature
oligodendrocyte have been investigated in detail by using stage-specific antibodies …

Oligodendrocyte precursor cells withdraw from the cell cycle and terminally differentiate after
a limited number of cell divisions. The timing of cell-cycle withdrawal and differentiation is …

The conditioned medium from B104 neuroblastoma cells (B104CM) induces proliferation of
oligodendrocyte progenitor cells (OPCs) in vitro. However, the molecular events that occur …

In our attempts to understand how the balance between self‐renewal and differentiation is
regulated in dividing precursor cells, we have discovered that intracellular redox state …

Background Periventricular white matter injury (PWMI) is a common form of brain injury
sustained by preterm infants. A major factor that predisposes to PWMI is hypoxia. Because …

Basic fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF) are mitogens
for bipotential oligodendrocyte-type 2 astrocyte (O-2A) progenitor cells. We investigated the …