Nano-scale analysis of synapse morphology in an autism mouse model with 15q11-13 copy number variation using focused ion beam milling and scanning electron …
Y Sato, S Okabe - Microscopy, 2019 - academic.oup.com
Circuit-level alternations in patients of autism spectrum disorder (ASD) is under active
investigation and detailed characterization of synapse morphology in ASD model mice …
investigation and detailed characterization of synapse morphology in ASD model mice …
Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain
MK Tripathi, SK Ojha, M Kartawy, I Khaliulin… - Scientific Reports, 2024 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder based on synaptic
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …
[HTML][HTML] Changes in the number and morphology of dendritic spines in the hippocampus and prefrontal cortex of the C58/J mouse model of autism
I Barón-Mendoza, E Maqueda-Martínez… - Frontiers in Cellular …, 2021 - frontiersin.org
Autism spectrum disorder (ASD) has a broad range of neurobiological characteristics,
including alterations in dendritic spines, where approximately 90% of excitatory synapses …
including alterations in dendritic spines, where approximately 90% of excitatory synapses …
Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models
Abstract Background Autism spectrum disorders (ASDs) are a heterogeneous group of
behaviorally defined disorders and are associated with hundreds of rare genetic mutations …
behaviorally defined disorders and are associated with hundreds of rare genetic mutations …
Imaging neural circuit pathology of autism spectrum disorders: autism-associated genes, animal models and the application of in vivo two-photon imaging
H Terashima, K Minatohara, H Maruoka, S Okabe - Microscopy, 2022 - academic.oup.com
Recent advances in human genetics identified genetic variants involved in causing autism
spectrum disorders (ASDs). Mouse models that mimic mutations found in patients with ASD …
spectrum disorders (ASDs). Mouse models that mimic mutations found in patients with ASD …
[HTML][HTML] Genetic aspects of autism spectrum disorders: insights from animal models
S Banerjee, M Riordan, MA Bhat - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are a complex neurodevelopmental disorder that display
a triad of core behavioral deficits including restricted interests, often accompanied by …
a triad of core behavioral deficits including restricted interests, often accompanied by …
Distinct defects in spine formation or pruning in two gene duplication mouse models of autism
Autism spectrum disorder (ASD) encompasses a complex set of developmental neurological
disorders, characterized by deficits in social communication and excessive repetitive …
disorders, characterized by deficits in social communication and excessive repetitive …
Identification of the common neurobiological process disturbed in genetic and non-genetic models for autism spectrum disorders
S Malijauskaite, AK Sauer, SE Hickey… - Cellular and Molecular …, 2022 - Springer
Autism spectrum disorders (ASD) are neurodevelopmental disorders. Genetic factors, along
with non-genetic triggers, have been shown to play a causative role. Despite the various …
with non-genetic triggers, have been shown to play a causative role. Despite the various …
[PDF][PDF] Cellular phenotypes in human iPSC-derived neurons from a genetic model of autism spectrum disorder
A deletion or duplication in the 16p11. 2 region is associated with neurodevelopmental
disorders, including autism spectrum disorder and schizophrenia. In addition to clinical …
disorders, including autism spectrum disorder and schizophrenia. In addition to clinical …
Enhanced synapse remodelling as a common phenotype in mouse models of autism
M Isshiki, S Tanaka, T Kuriu, K Tabuchi… - Nature …, 2014 - nature.com
Developmental deficits in neuronal connectivity are considered to be present in patients with
autism spectrum disorders (ASDs). Here we examine this possibility by using in vivo spine …
autism spectrum disorders (ASDs). Here we examine this possibility by using in vivo spine …