Donor chimaerism is a strong indicator of disease free survival following bone marrow transplantation for chronic myeloid leukaemia.

N GARDINER, M LAWLER… - Leukemia …, 1997 - search.ebscohost.com
Abstract Although Chronic Myeloid Leukaemia (CML) can be treated successfully with
allogeneic bone marrow transplantation (BMT), leukaemia relapse remains a significant …

Persistent donor chimaerism is consistent with disease-free survival following BMT for chronic myeloid leukaemia

N Gardiner, M Lawler, J O'Riordan, M DeArce… - Bone marrow …, 1997 - nature.com
Chronic myeloid leukaemia (CML) can be treated successfully with allogeneic bone marrow
transplantation (BMT) leading to long-term disease-free survival. Leukemia relapse …

Importance of mixed chimerism to predict relapse in persistently BCR/ABL positive long survivors after allogeneic bone marrow transplantation for chronic myeloid …

J Roman, C Martin, A Torres, A Garcia… - Leukemia & …, 1998 - Taylor & Francis
Determination of hematological chimerism could be helpful in understanding the biology of
leukemic relapse after allogeneic bone marrow transplant (BMT) for chronic myeloid …

Molecular analysis of lineage-specific chimerism and minimal residual disease by RT-PCR of p210BCR-ABL and p190BCR-ABL after allogeneic bone marrow transplantation …

J Serrano, J Roman, J Sanchez… - Blood, The Journal …, 2000 - ashpublications.org
We studied lineage-specific chimerism and minimal residual disease (MRD) in sequential
posttransplant samples from 55 patients who underwent unmanipulated (n= 44) or partially T …

Sequential molecular monitoring of chimerism in chronic myeloid leukemia patients receiving donor lymphocyte transfusion for relapse after bone marrow …

MC Rapanotti, W Arcese, S Buffolino, AP Iori… - Bone marrow …, 1997 - nature.com
Recent observations of chimerism in patients relapsed following an allotransplant suggest
the persistence of immunotolerance, thus offering a biologic rationale for the use of donor …

Minimal residual disease is more common in patients who have mixed T-cell chimerism after bone marrow transplantation for chronic myelogenous leukemia

S Mackinnon, L Barnett, G Heller, RJ O'Reilly - 1994 - ashpublications.org
Determining both lymphoid chimerism and the presence of minimal residual disease after
allogeneic bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) …

Prediction and reversion of post-transplant relapse in patients with chronic myeloid leukemia using mixed chimerism and residual disease detection and adoptive …

R Formánková, L Honzátková, J Moravcová… - Leukemia research, 2000 - Elsevier
In the prospective study, we examined hematopoietic mixed chimerism (using polymerase
chain reaction (PCR) of variable number of tandem repeat-VNTR sequences) and minimal …

A comparison of chimerism and minimal residual disease between four different allogeneic transplantation methods in patients with chronic myelogenous leukemia in …

AH Elmaagacli, K Runkel, N Steckel, B Opalka… - Bone marrow …, 2001 - nature.com
The detection of chimerism, residual molecular and cytogenetic disease following
transplantation of peripheral blood stem cells (PBSCT) with a nonmyeloablative conditioning …

Lineage-specific chimaerism quantification after T-cell depleted peripheral blood stem cell transplantation

I Buño, B Anta, E Moreno-López… - Leukemia & …, 2003 - Taylor & Francis
Patients that receive a T-cell depleted (TCD) hematopoietic stem cell transplantation (SCT)
show higher risk of graft failure/rejection and of disease relapse than those that receive …

A second unrelated bone marrow transplant: successful quantitative monitoring of mixed chimerism using a highly discriminative PCR‐STR system

IW Blau, N Basara, A Serr, C Seidl… - Clinical & Laboratory …, 1999 - Wiley Online Library
A second bone marrow transplant (BMT) might be considered as an option in patients with
leukaemia with graft failure after BMT. We report the successful treatment of a patient with …