[HTML][HTML] A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid …

KJ Liu, TY Chao, JY Chang, AL Cheng… - Journal of biomedical …, 2016 - Springer
Background To better evaluate and improve the efficacy of dendritic cell (DC)-based cancer
immunotherapy, we conducted a clinical study of patients with advanced colorectal cancer …

Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive …

A Tamir, E Basagila, A Kagahzian, L Jiao… - Cancer Immunology …, 2007 - Springer
Abstract Background Dendritic cells (DCs) are the most effective antigen-presenting cells. In
the last decade, the use of DCs for immunotherapy of cancer patients has been vastly …

Clinical responses in patients with advanced colorectal cancer to a dendritic cell based vaccine

SK Burgdorf, A Fischer, PS Myschetzky… - Oncology …, 2008 - spandidos-publications.com
Patients with disseminated colorectal cancer have a poor prognosis. Preliminary studies
have shown encouraging results from vaccines based on dendritic cells. The aim of this …

Generation of carcinoembryonic antigen (CEA)-specific T-cell responses in HLA-A* 0201 and HLA-A* 2402 late-stage colorectal cancer patients after vaccination with …

KJ Liu, CC Wang, LT Chen, AL Cheng, DT Lin… - Clinical cancer …, 2004 - AACR
Purpose: We intranodally immunized metastatic colorectal carcinoma patients, who had
failed standard chemotherapy, with dendritic cells (DCs) pulsed with HLA-A* 0201-or HLA …

Comprehensive immunological analyses of colorectal cancer patients in the phase I/II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic …

M Sakakibara, T Kanto, M Hayakawa, S Kuroda… - Cancer Immunology …, 2011 - Springer
Dendritic cell (DC) vaccine has been used to treat patients with advanced colorectal cancer
(CRC). The results of vaccine-induced clinical responses have not always been satisfactory …

[HTML][HTML] Vaccination of colorectal cancer patients with CEA-loaded dendritic cells: antigen-specific T cell responses in DTH skin tests

WJ Lesterhuis, IJM De Vries, DH Schuurhuis… - Annals of …, 2006 - Elsevier
Abstract Background Dendritic cells (DCs) are the professional antigen-presenting cells of
the immune system. As such they are currently used in clinical vaccination protocols in …

Dendritic cell vaccine in addition to FOLFIRI regimen improve antitumor effects through the inhibition of immunosuppressive cells in murine colorectal cancer model

HS Kim, HM Park, JS Park, HJ Sohn, SG Kim, HJ Kim… - Vaccine, 2010 - Elsevier
Although chemotherapy is still one of the best treatments for most cancers, immunotherapies
such as dendritic cell (DC) vaccines have emerged as an alternative protocol for destroying …

Long-term vaccine therapy with autologous whole tumor cell-pulsed dendritic cells for a patient with recurrent rectal carcinoma

H Onishi, T Morisaki, E Baba, M Nakamura… - Anticancer …, 2011 - ar.iiarjournals.org
We performed continuous dendritic cells (DCs) vaccination to treat a patient with
chemotherapy-resistant recurrent rectal carcinoma and lung and bone metastases. A patient …

Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides

B Kavanagh, A Ko, A Venook, K Margolin… - Journal of …, 2007 - journals.lww.com
Developing a process to generate dendritic cells (DCs) applicable for multicenter trials
would facilitate cancer vaccine development. Moreover, targeting multiple antigens with …

Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded …

J Babatz, C Röllig, B Löbel, G Folprecht… - Cancer Immunology …, 2006 - Springer
Abstract Purpose: Dendritic cells (DCs) are characterized by their extraordinary capacity to
induce T-cell responses, providing the opportunity of DC-based cancer vaccination …